Shubhendu Palei
Also known as: Chemical Biology, Epigenetics, protein chemistry, cyclic peptides
IIT Kharagpur, Athebio AG (Start up Company), Westfälische Wilhelms-Universität Münster, ETH Zurich
0000-0003-4447-7022
About
We are a young research group at IIT Kharagpur having interests in interdisciplinary areas of Chemical Biology. We are trying to implement the fundamentals of chemical biology tools to manipulate biological system in vitro and in vivo. This would allow to understand the biochemical processes on molecular level and provide tremendous opportunity to develop novel biochemical probes for studying such processes. Main areas of our research group are chemical epigenetics, histone PTMs, genetic code expansion, cyclic peptides, inteins, directed evolution.
Employment
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IIT Kharagpur Assistant Professor2024 - Present
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Athebio AG (Start up Company) Senior Scientist2023 - 2023
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ETH Zurich Postdoctoral Researcher2021 - 2022
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Technical University of Dortmund Post-doctoral Researcher2018 - 2021
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Westfälische Wilhelms-Universität Münster Post-doctoral Researcher2017 - 2017
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Westfälische Wilhelms-Universität Münster Doctoral Researcher2012 - 2017
Education
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Westfälische Wilhelms-Universität Münster Ph. D.2012 - 2017
Projects & Funding
Projects & funding information is unavailable.
Publications (16)
- Light‐Activatable Ubiquitin for Studying Linkage‐Specific Ubiquitin Chain Formation Kinetics Save
- Synthesis, SAR, and application of JQ1 analogs as PROTACs for cancer therapy Save
- Correction: A high-throughput effector screen identifies a novel small molecule scaffold for inhibition of ten-eleven translocation dioxygenase 2 Save
- Optochemical Control of TET Dioxygenases Enables Kinetic Insights into the Domain-Dependent Interplay of TET1 and MBD1 while Oxidizing and Reading 5-Methylcytosine Save
- Evolved DNA Duplex Readers for Strand-Asymmetrically Modified 5-Hydroxymethylcytosine/5-Methylcytosine CpG Dyads Save
- Preparation of Bacterial Cell-Surface Displayed Semisynthetic Cyclic Peptides. Save
- A high-throughput effector screen identifies a novel small molecule scaffold for inhibition of ten-eleven translocation dioxygenase 2 Save
- Light-Activation of DNA-Methyltransferases. Save
- Semisynthetic head-to-tail cyclized peptides obtained by combining protein trans-splicing and intramolecular expressed protein ligation Save
- Light-Activatable TET-Dioxygenases Reveal Dynamics of 5-Methylcytosine Oxidation and Transcriptome Reorganization. Save