Jay Prakash Kumar, PhD

About

I am a creative, curious, and self-motivated Research Instructor with an eagerness to learn about cryo-EM, drug discovery, and development.

Employment

• Vanderbilt University Research Instructor
  2026 - Present
• National Cancer Institute Postdoctoral researcher
  2019 - 2025
• Institute for Stem Cell Science and Regenerative Medicine Bridging Post Doctoral Fellow @ inStem (NCBS-TIFR)
  2018 - 2019

Education

• Institute for Stem Cell Science and Regenerative Medicine Ph.D student
  2012 - 2018
• VIT University M.Sc-Biotechnology
  2010 - 2012
• St. Xavier's College B.Sc. (Hons.) Biotechnology
  2007 - 2010

Projects & Funding

Projects & funding information is unavailable.

Publications (10)

• Crystal structure and mechanistic studies of the PPM1D serine/threonine phosphatase catalytic domain
  Journal of Biological Chemistry 2024 DOI: 10.1016/j.jbc.2024.107561
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• Alkyl-substituted N-methylaryl-N′-aryl-4-aminobenzamides: A new series of small molecule inhibitors for Wip1 phosphatase
  European Journal of Medicinal Chemistry 2022 DOI: 10.1016/j.ejmech.2022.114763
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• Crystal structures and kinetics of N-acetylneuraminate lyase from Fusobacterium nucleatum
  Acta Crystallographica Section F Structural Biology Communications 2018 DOI: 10.1107/S2053230X18012992
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• Conformational transitions of the sodium-dependent sugar transporter, vSGLT.
  Proceedings of the National Academy of Sciences of the United States of America 2018 DOI: 10.1073/pnas.1718451115
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• Automation aided optimization of cloning, expression and purification of enzymes of the bacterial sialic acid catabolic and sialylation pathways enzymes for structural studies
  Microbial Biotechnology 2018 DOI: 10.1111/1751-7915.13041
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• Combinatorial Pairwise Assembly Efficiently Generates High Affinity Binders and Enables a "Mix-and-Read" Detection Scheme.
  ACS synthetic biology 2016 DOI: 10.1021/acssynbio.6b00034
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• Identification of Conformation Specific Binder for the NA(+)/Galactose Transporter
  Biophysical Journal 2016 DOI: 10.1016/J.BPJ.2015.11.388
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• Revealing the Transport Cycle Dynamics of the Sodium Dependent Sugar Transporter by Double Electron-Electron Resonance and Wide-Angle X-ray Scattering
  Biophysical Journal 2016 DOI: 10.1016/J.BPJ.2015.11.1228
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• Identification of a second substrate-binding Site in solute-sodium symporters
  Journal of Biological Chemistry 2015 DOI: 10.1074/jbc.M114.584383
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• Identification of a second substrate-binding site in solute-sodium symporters (vol 290, pg 127, 2015)
  Journal of Biological Chemistry 2015 DOI: 10.1074/JBC.A114.584383
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