Krishan Gopal Thakur

Employment

• National Institute of Pharmaceutical Education and Research Professor
  2025 - Present
• CSIR-Institute of Microbial Technology Senior Principal Scientist
  2024 - Present
• CSIR - Institute of Microbial Technology Principal Scientist
  2019 - 2024
• CSIR - Institute of Microbial Technology Senior Scientist
  2016 - 2019
• CSIR - Institute of Microbial Technology Scientist
  2011 - 2016
• Indian Institute of Science Research Associate
  2009 - 2011

Education

• Indian Institute of Science Ph.D.
  2003 - 2009
• Central Research Institute M. Sc. (Microbiology)
  2000 - 2002
• Government Degree College B. Sc.
  1997 - 2000

Projects & Funding

Projects & funding information is unavailable.

Publications (69)

• Development of Benzimidazole-Based BZ-30 as an Orally Bioavailable Broad-Spectrum Inhibitor of SARS-CoV-2.
  Journal of medicinal chemistry 2026 DOI: 10.1021/acs.jmedchem.6c00365
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• Structural and functional characterization of VapBC52 toxin–antitoxin system from Mycobacterium tuberculosis
  Nucleic Acids Research 2026 DOI: 10.1093/nar/gkag611
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• Discovery of Conformationally Constrained Dihydro Benzo-Indole Derivatives as Metallo-β-Lactamase Inhibitors to Tackle Multidrug-Resistant Bacterial Infections
  Journal of Medicinal Chemistry 2025 DOI: 10.1021/acs.jmedchem.4c02207
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• Itaconate mechanism of action and dissimilation in Mycobacterium tuberculosis
  Proceedings of the National Academy of Sciences 2025 DOI: 10.1073/pnas.2423114122
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• Identification and Characterization of a Novel Protein–Protein Interaction Among SARS‐CoV‐2 Nucleocapsid, Host SFPQ, and hnRNP U and Its Potential Role in Virus Replication
  Biology of the Cell 2025 DOI: 10.1111/boc.70008
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• Strategic Design and Optimization of Umifenovir Analogues: Balancing Antiviral Efficacy and hERG Toxicity against SARS-CoV-2
  Journal of Medicinal Chemistry 2025 DOI: 10.1021/acs.jmedchem.4c03093
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• 9-fluorenone-based synthetic sulfonamide compounds as dual inhibitors of SARS-CoV-2 Main-Protease and Papain-like Protease.
  Molecular diversity 2025 DOI: 10.1007/s11030-025-11315-2
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• The role of amino acid composition in the antibacterial activity of laterosporulin analogs
  Journal of Applied Microbiology 2025 DOI: 10.1093/jambio/lxaf208
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• Spike conformational and glycan heterogeneity associated with furin cleavage causes incomplete neutralization of SARS-CoV-2
  Nature Communications 2025 DOI: 10.1038/s41467-025-65099-y
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• The yxiD gene from Bacillus subtilis 6633 encodes a polymorphic toxin with tRNase activity and is neutralized by the cognate immunity protein YxxD
  Nucleic Acids Research 2025 DOI: 10.1093/nar/gkaf1321
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