CL
Chi Keung Lam
Also known as: Lam
University of Delaware, University of Cincinnati, Purdue University West Lafayette
Research areas: Medicine · Cardiology and Cardiovascular Medicine · Cardiac electrophysiology and arrhythmias · Cardiomyopathy and Myosin Studies · Pluripotent Stem Cells Research
0000-0003-4565-9426
Employment
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University of Delaware Assistant Professor2021 - Present
Education
- 2007 - 2012
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Purdue University B.S.2003 - 2007
Projects & Funding
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Dissecting the Pathogenesis of Presenilin-2 Mutation in Dilated Cardiomyopathy American Heart Association2019 - 2022
Publications (34)
- Application of Calcium Kinetics Characterization in Cardiac Disease Modeling and Drug Discovery Save
- Defective Biomechanics and Pharmacological Rescue of Human Cardiomyocytes with Filamin C Truncations Save
- Filamin C Deficiency Impairs Sarcomere Stability and Activates Focal Adhesion Kinase through PDGFRA Signaling in Induced Pluripotent Stem Cell-Derived Cardiomyocytes Save
- CaMKII: Therapeutic target in vascular diseases warranted for Clinical and Translational Discovery? Save
- Activation of PDGFRA signaling contributes to filamin C–related arrhythmogenic cardiomyopathy Save
- The Potential of Hsp90 in Targeting Pathological Pathways in Cardiac Diseases Save
- The Potential of Gamma Secretase as a Therapeutic Target for Cardiac Diseases Save
- Clinical Trial in a Dish Save
- Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes. Save
- Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Save
- Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients. Save
- Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. Save
- Identifying the Transcriptome Signatures of Calcium Channel Blockers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Save
- Human-Induced Pluripotent Stem Cell Model of Trastuzumab-Induced Cardiac Dysfunction in Patients With Breast Cancer. Save
- A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles. Save
- A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay. Save
- Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human-Induced Pluripotent Stem Cells. Save
- Disease modelling and drug discovery for hypertrophic cardiomyopathy using pluripotent stem cells: how far have we come? Save
- Genome Editing of Induced Pluripotent Stem Cells to Decipher Cardiac Channelopathy Variant. Save
- A novel human S10F-Hsp20 mutation induces lethal peripartum cardiomyopathy. Save