Bharvi Sharma

About

Bharvi Sharma is a researcher specializing in synthetic organic chemistry, Lipid Chemistry, click chemistry, mRNA delivery, medicinal chemistry, and bioconjugation. Her research interests focus on the development and application of innovative chemical strategies for biologically relevant molecules and therapeutic applications. Her current research interests include advanced click reactions, bioconjugation chemistry, ADCs, LNPs and the development of chemical tools for biomedical applications.

Employment

• Poseida Therapeutics (United States) Research Scientist
  2024 - 2026
• AxisPharm Scientist -I
  2022 - 2024
• Khalsa College for Women Assistant professor
  2015 - 2016

Education

• Guru Nanak Dev University M.S. (Honors School)
  2013 - 2015
• Guru Nanak Dev University B.S. (Honors School) Chemistry
  2010 - 2013

Projects & Funding

Projects & funding information is unavailable.

Publications (10)

• Designing quinoline-isoniazid hybrids as potent anti-tubercular agents inhibiting mycolic acid biosynthesis
  European Journal of Medicinal Chemistry 2022 DOI: 10.1016/j.ejmech.2022.114531
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• Functionalized 3-hydroxy-3-aminoquinoline-oxindole hybrids as promising dual-function anti-plasmodials
  European Journal of Medicinal Chemistry Reports 2022 DOI: 10.1016/j.ejmcr.2022.100052
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• Has Ferrocene Really Delivered Its Role in Accentuating the Bioactivity of Organic Scaffolds?
  Journal of Medicinal Chemistry 2021 DOI: 10.1021/acs.jmedchem.1c00390
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• 1 H ‐1,2,3‐triazole embedded Isatin‐Benzaldehyde‐bis(heteronuclearhydrazones): design, synthesis, antimycobacterial, and cytotoxic evaluation
  Chemical Biology & Drug Design 2021 DOI: 10.1111/cbdd.13984
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• Recent accomplishments on the synthetic/biological facets of pharmacologically active 1H-1,2,3-triazoles
  European Journal of Medicinal Chemistry 2021 DOI: 10.1016/j.ejmech.2020.113069
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• Design, Synthesis, Antiproliferative Evaluation, and Molecular Docking Studies of N-(3-Hydroxyindole)-Appended β-Carbolines/Tetrahydro-β-Carbolines Targeting Triple-Negative and Non-Triple-Negative Breast Cancer
  ACS Omega 2020 DOI: 10.1021/acsomega.0c01226
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• Synthesis, anti-plasmodial and cytotoxic evaluation of 1H-1,2,3-triazole/acyl hydrazide integrated tetrahydro-β-carboline-4-aminoquinoline conjugates
  Bioorganic & Medicinal Chemistry Letters 2020 DOI: 10.1016/j.bmcl.2019.126810
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• Design, synthesis, and anti-proliferative evaluation of 1H-1,2,3-triazole grafted tetrahydro-β-carboline-chalcone/ferrocenylchalcone conjugates in estrogen responsive and triple negative breast cancer cells
  New Journal of Chemistry 2020 DOI: 10.1039/d0nj00879f
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• Diastereoselective approach to rationally design tetrahydro-β-carboline–isatin conjugates as potential SERMs against breast cancer
  RSC Advances 2019 DOI: 10.1039/c9ra00744j
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• β -Lactam-Synthon Interceded Diastereoselective Synthesis of 2-Azido-γ -amino Alcohols with Subsequent Transformations to Functionally Enriched Heterocycles
  ChemistrySelect 2018 DOI: 10.1002/slct.201800512
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