Ananda Pal

About

I am a Technical Officer-C at the ICMR-National Institute for Research in Bacterial Infections, India, working in the Division of Clinical Medicine. My work focuses on supporting translational and clinical research through advanced laboratory techniques, animal experimentation, molecular biology, immunology, microbiology, and flow cytometry. I am actively involved in the development and maintenance of animal models, including diabetic foot ulcer, wound infection, and immunization models for vaccine and therapeutic research. I also have experience in the operation of advanced flow cytometry platforms and other high-end research instruments.
I am currently pursuing a Ph.D. in Medical Research under the Academy of Scientific and Innovative Research. My doctoral research focuses on the application of bacteriophages as alternative therapeutic agents against multidrug-resistant bacterial pathogens, particularly in chronic wound and diabetic foot ulcer infections. My research integrates microbiology, molecular biology, host–pathogen interaction studies, biofilm biology, and translational research approaches to address the growing challenge of antimicrobial resistance (AMR).My scientific interests lie in understanding the interactions between bacteriophages, bacterial pathogens, and host immune responses, with a particular emphasis on developing innovative phage-based therapeutics for combating multidrug-resistant infections. I am especially interested in translating laboratory findings into clinically relevant interventions that can improve treatment outcomes for patients suffering from chronic wound and diabetic foot ulcer infections.
To enhance my research expertise and foster international scientific collaboration, I actively seek opportunities for short-term research exchanges, advanced training programs, and collaborative projects. These experiences provide exposure to cutting-edge technologies and methodologies, strengthen interdisciplinary research skills, facilitate knowledge exchange, and promote global scientific networking. Such interactions play a vital role in my professional development and contribute to the advancement of innovative solutions for infectious disease management.In addition to research activities, I contribute to laboratory management, procurement of scientific equipment and reagents, maintenance of high-end research infrastructure, and the smooth execution of intramural and extramural research projects. My long-term goal is to contribute to the development of novel phage-based and antimicrobial strategies against multidrug-resistant pathogens and to support high-quality biomedical research that advances public health and infectious disease control.

Employment

• ICMR-National Institute for Research in Bacterial Infections Technical Officer-C
  2022 - Present
• National Institute of Cholera and Enteric Diseases Technical Officer-B
  2017 - 2022
• National Institute of Cholera and Enteric Diseases Technical Officer-A
  2012 - 2017
• National Institute of Cholera and Enteric Diseases Technical Assistant
  2006 - 2012
• Institute of Post Graduate Medical Education and Research Medical Lab Technologist
  2005 - 2006

Education

• State Medical faculty of West Bengal Diploma In Medical Laboratory Technology (Tech)
  2002 - 2004
• Jadavpur University Post Graduate Diploma In Instrumental Techniques in Chemical Analysis
  2001 - 2002
• Calcutta University Bachelor In Science (Honors),Chemistry
  1996 - 1999

Projects & Funding

Projects & funding information is unavailable.

Publications (10)

• A peptide-induced regression of low-grade malignant breast tumor via activation of autophagy in breast cancer cells
  Molecular Medicine 2026 DOI: 10.1186/s10020-026-01514-4
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• FliC adjuvant augments protective efficacy of recombinant T2544 antigen against SalmonellaTyphiand Paratyphi A by increasing serum antibodies, intestinal secretory immunoglobulin A and T cell memory.
  Vaccine 2025 DOI: 10.1016/j.vaccine.2025.127767
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• Salmonella Typhi serine threonine kinase T4519 induces lysosomal membrane permeabilization by manipulating Toll-like receptor 2-Cystatin B-Cathepsin B-NF-κB-reactive oxygen species pathway and promotes survival within human macrophages.
  PLoS pathogens 2025 DOI: 10.1371/journal.ppat.1013041
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• Metallo-protease Peptidase M84 from Bacillusaltitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1.
  iScience 2024 DOI: 10.1016/j.isci.2024.109828
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• Intranasal immunization of mice with chimera of Salmonella Typhi protein elicits protective intestinal immunity
  npj Vaccines 2024 DOI: 10.1038/s41541-024-00812-4
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• A candidate glycoconjugate vaccine induces protective antibodies in the serum and intestinal secretions, antibody recall response and memory T cells and protects against both typhoidal and non-typhoidal Salmonella serovars.
  Frontiers in immunology 2024 DOI: 10.3389/fimmu.2023.1304170
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• Subtilisin from Bacillus amyloliquefaciens induces apoptosis in breast cancer cells through ubiquitin-proteasome-mediated tubulin degradation.
  International journal of biological macromolecules 2022 DOI: 10.1016/j.ijbiomac.2022.08.086
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• Macrophage Cell Lines and Murine Infection by Salmonella enterica Serovar Typhi L-Form Bacteria.
  Infection and immunity 2022 DOI: 10.1128/iai.00119-22
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• Salmonella Typhi outer membrane protein STIV is a potential candidate for vaccine development against typhoid and paratyphoid fever.
  Immunobiology 2019 DOI: 10.1016/j.imbio.2019.02.011
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• Molecular targeting of breast and colon cancer cells by PAR1 mediated apoptosis through a novel pro-apoptotic peptide.
  Apoptosis : an international journal on programmed cell death 2018 DOI: 10.1007/s10495-018-1485-4
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