Jian Tajbakhsh

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Publications (19)

• DNA methylation topology differentiates between normal and malignant in cell models, resected human tissues, and exfoliated sputum cells of lung epithelium.
  Frontiers in oncology 2022 DOI: 10.3389/fonc.2022.991120
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• Highly sensitive noninvasive early lung cancer detection using DNA methylation topology in sputum-derived epithelial cells.
  JTCVS open 2022 DOI: 10.1016/j.xjon.2022.11.018
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• Covisualization of Global DNA Methylation/Hydroxymethylation and Protein Biomarkers for Ultrahigh-Definition Epigenetic Phenotyping of Stem Cells.
  Methods in molecular biology (Clifton, N.J.) 2020 DOI: 10.1007/7651_2019_276
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• An Inhibitor of GSK3B and HDACs Kills Pancreatic Cancer Cells and Slows Pancreatic Tumor Growth and Metastasis in Mice.
  Gastroenterology 2018 DOI: 10.1053/j.gastro.2018.08.028
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• Prostate cancer diagnosis using epigenetic biomarkers, 3D high-content imaging and probabilistic cell-by-cell classifiers.
  Oncotarget 2017 DOI: 10.18632/oncotarget.18985
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• Rapid 3-D delineation of cell nuclei for high-content screening platforms.
  Computers in biology and medicine 2015 DOI: 10.1016/j.compbiomed.2015.04.025
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• Dynamic heterogeneity of DNA methylation and hydroxymethylation in embryonic stem cell populations captured by single-cell 3D high-content analysis.
  Experimental cell research 2015 DOI: 10.1016/j.yexcr.2015.02.004
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• Covisualization of methylcytosine, global DNA, and protein biomarkers for In Situ 3D DNA methylation phenotyping of stem cells.
  Methods in molecular biology (Clifton, N.J.) 2013 DOI: 10.1007/7651_2013_18
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• 3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models.
  BMC pharmacology & toxicology 2013 DOI: 10.1186/2050-6511-14-11
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• Nuclear DNA methylation and chromatin condensation phenotypes are distinct between normally proliferating/aging, rapidly growing/immortal, and senescent cells.
  Oncotarget 2013 DOI: 10.18632/oncotarget.942
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