Manisha Arkile-Shingare

Employment

• University of California, Santa Cruz Assistant research specialist -III
  2019 - 2022
• Lupin Pharmaceuticals (India) Senior Research associates
  2015 - 2018
• National Chemical Laboratory senior project fellow
  2013 - 2015
• Manshya envirobiotech pvt ltd Microbiologist
  2012 - 2013
• Anmol minral,s private limited Microbiologist
  2010 - 2011

Education

• Savitribai Phule Pune University M.Sc.
  2008 - 2010
• Savitribai Phule Pune University B.Sc Microbiology
  2008 - 2008

Projects & Funding

Projects & funding information is unavailable.

Publications (18)

• HDAC activity is dispensable for repression of cell-cycle genes by DREAM and E2F:RB complexes
  Nature Communications 2024 DOI: 10.1038/s41467-024-48724-0
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• HDAC activity is dispensable for repression of cell-cycle genes by DREAM and E2F:RB complexes
  2023 DOI: 10.1101/2023.10.28.564489
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• Dual PI3Kδγ inhibition demonstrates potent anticancer effects in diffuse large B-cell lymphoma models: Discovery and preclinical characterization of LL-00084282
  Biochemical and Biophysical Research Communications 2022 DOI: 10.1016/j.bbrc.2022.11.038
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• Discovery of a Potent and Selective PI3Kδ Inhibitor (S)-2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl-4H-quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Ca…
  Journal of Medicinal Chemistry 2020 DOI: 10.1021/acs.jmedchem.0c01264
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• Recursive Partitioning Analysis and Anti-Tubercular Screening of 3- Aminopyrazine-2-Carbohydrazide Derivatives
  Letters in Drug Design & Discovery 2019 DOI: 10.2174/1570180816666190329222636
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• Editorial: Medicinal Chemistry Research in India
  ACS Medicinal Chemistry Letters 2017 DOI: 10.1021/acsmedchemlett.7b00064
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• Synthesis and Antitubercular activity of New Thiazolidinones with Pyrazinyl and Thiazolyl Scaffolds
  Journal of Heterocyclic Chemistry 2017 DOI: 10.1002/jhet.2552
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• Synthesis of Novel Triazole‐incorporated Isatin Derivatives as Antifungal, Antitubercular, and Antioxidant Agents and Molecular Docking Study
  Journal of Heterocyclic Chemistry 2017 DOI: 10.1002/jhet.2598
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• Design, synthesis and biological evaluation of novel azaspiro analogs of linezolid as antibacterial and antitubercular agents
  European Journal of Medicinal Chemistry 2016 DOI: 10.1016/j.ejmech.2016.07.001
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• Synthesis and bioactivity of novel triazole incorporated benzothiazinone derivatives as antitubercular and antioxidant agent
  Bioorganic & Medicinal Chemistry Letters 2016 DOI: 10.1016/j.bmcl.2015.11.071
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