Camille GRANDCLEMENT

Employment

• Onward Therapeutics Director Project Evaluation and Pre-clinical Development
  2023 - Present
• Ichnos Sciences Principal Scientist
  2018 - 2023
• TransCure BioServices (France) Project Director
  2016 - 2018

Education

• University of Franche-Comté PhD Molecular Oncology
  2007 - 2011
• University of Franche-Comté PharmD
  2001 - 2007

Projects & Funding

Projects & funding information is unavailable.

Publications (15)

• Development of ISB 1442, a CD38 and CD47 bispecific biparatopic antibody innate cell modulator for the treatment of multiple myeloma
  Nature Communications 2024 DOI: 10.1038/s41467-024-46310-y
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• P871: ISB 1442, A FIRST-IN-CLASS CD38 AND CD47 BISPECIFIC ANTIBODY INNATE CELL MODULATOR FOR THE TREATMENT OF CD38 POSITIVE HEMATOLOGICAL MALIGNANCIES
  HemaSphere 2022
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• Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis.
  Nature communications 2017 DOI: 10.1038/s41467-017-00678-2
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• The Transcription Factor Tcf1 Contributes to Normal NK Cell Development and Function by Limiting the Expression of Granzymes.
  Cell reports 2017 DOI: 10.1016/j.celrep.2017.06.071
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• Activation by SLAM Family Receptors Contributes to NK Cell Mediated "Missing-Self" Recognition.
  PloS one 2016 DOI: 10.1371/journal.pone.0153236
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• NK Cells Respond to Haptens by the Activation of Calcium Permeable Plasma Membrane Channels.
  PloS one 2016 DOI: 10.1371/journal.pone.0151031
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• Modulation of mTOR Signalling Triggers the Formation of Stem Cell-like Memory T Cells.
  EBioMedicine 2016 DOI: 10.1016/j.ebiom.2016.01.019
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• Adaptations of Natural Killer Cells to Self-MHC Class I.
  Frontiers in immunology 2014 DOI: 10.3389/fimmu.2014.00349
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• Inhibitory receptor-mediated regulation of natural killer cells.
  Critical reviews in immunology 2014 DOI: 10.1615/critrevimmunol.2014012220
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• Opposing Mcl-1, the GALIG proapoptotic gene is upregulated as neutrophils die and underexpressed in Acute Myeloid Leukemia cells.
  Molecular immunology 2013 DOI: 10.1016/j.molimm.2013.04.012
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