IW
Ian Weidling
University of Kansas Medical Center, AbbVie Canada (Canada)
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Alzheimer's disease research and treatments · Mitochondrial Function and Pathology · Autophagy in Disease and Therapy
0009-0009-5277-7149
Employment
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University of Kansas Medical Center Postdoctoral fellow2024 - Present
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AbbVie Senior Scientist II2023 - 2024
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AbbVie Postdoctoral fellow2020 - 2023
Education
- 2015 - 2019
Projects & Funding
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Mitochondrial effects on 4R Tau expression University of Kansas Endowment2025 - 2026
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Mitochondrial modeling of Alzheimer's disease NIA2025 - 2026
Publications (19)
- Chronic mitochondrial DNA depletion alters MAPT splicing and increases tau levels Save
- An aging hallmark, Alzheimer's disease, and APOE nexus Save
- BMP, MEK, and WNT inhibition with NGN2 expression for rapid generation of hiPSC-derived neurons amenable to regional patterning. Save
- hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation. Save
- Inhibiting mtDNA transcript translation alters Alzheimer's disease-associated biology. Save
- Mitochondria Profoundly Influence Apolipoprotein E Biology. Save
- β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence. Save
- A ketogenic diet differentially affects neuron and astrocyte transcription. Save
- Detection of mitochondria-pertinent components in exosomes. Save
- Mitochondria in Alzheimer's disease and their potential role in Alzheimer's proteostasis. Save
- Mitochondrial DNA Manipulations Affect Tau Oligomerization. Save
- Mitochondrial Dysfunction and Stress Responses in Alzheimer's Disease. Save
- Effects of Microglial Cytokines on Alzheimer's Disease-Related Phenomena. Save
- A bioenergetics systems evaluation of ketogenic diet liver effects. Save
- Mitochondria-Derived Damage-Associated Molecular Patterns in Neurodegeneration. Save
- Mitochondria, Cybrids, Aging, and Alzheimer's Disease. Save
- Extracellular Mitochondria and Mitochondrial Components Act as Damage-Associated Molecular Pattern Molecules in the Mouse Brain. Save
- Oxaloacetate enhances neuronal cell bioenergetic fluxes and infrastructure. Save
- The ABCD's of 5'-adenosine monophosphate-activated protein kinase and adrenoleukodystrophy. Save