Naga Malleswara Rao Nakka
Research areas: Materials Science · Biomaterials · Nanoparticle-Based Drug Delivery · Pancreatic and Hepatic Oncology Research · Polymer Surface Interaction Studies
0009-0009-8360-1007
About
I am a dedicated and accomplished researcher with extensive experience in polymer chemistry, nanotechnology, and targeted drug and gene delivery systems. Currently serving as a Postdoctoral Research Associate at Mayo Clinic, Florida, USA. I specialize in the design, synthesis, and characterization of biodegradable and biocompatible polymers and advanced nanoformulations for cancer therapy, gene delivery, and vaccine applications.
My research integrates advanced polymerization techniques, including Ring-Opening Polymerization (ROP), Atom Transfer Radical Polymerization (ATRP), and Reversible Addition-Fragmentation Chain Transfer (RAFT) polymerization, with cutting-edge nanotechnology approaches to develop innovative nanomedicine platforms. I have extensive experience in the formulation and characterization of polymeric and lipid-based nanoparticles for targeted therapeutic delivery.
In addition to materials development, I possess strong expertise in in vitro and in vivo preclinical evaluation, including mammalian cell culture, cytotoxicity assays, cellular uptake studies, transfection studies, apoptosis assays, tumor xenograft models, biodistribution studies, and therapeutic efficacy assessment. I am proficient in a wide range of molecular and cellular biology techniques, including Western blotting, RT-PCR/qPCR, flow cytometry (FACS), ELISA, immunohistochemistry (IHC), immunofluorescence staining, confocal microscopy, protein and gene expression analysis, and tissue processing.
Throughout my career, I have led and contributed to multidisciplinary academic and industrial R&D projects, resulting in high-impact publications, patent development, and innovative therapeutic technologies. My expertise spans nanoparticle synthesis, analytical characterization, molecular biology, translational research, project management, scientific writing, grant support, and mentoring. I thrive in collaborative environments focused on advancing next-generation healthcare technologies and translating scientific discoveries into clinically relevant solutions
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