Macau University of Science and Technology
Research areas: Medicine · Surgery · Congenital gastrointestinal and neural anomalies · Pediatric Hepatobiliary Diseases and Treatments · Intestinal Malrotation and Obstruction Disorders
0000-0001-6231-3035
About
Professor Paul Tam graduated from the Medical School of The University of Hong Kong in 1976. He received his training and spent his early career years in the Department of Surgery of the University until 1986. He was Senior Lecturer at the University of Liverpool from 1986 to 1990, and Reader and Director of Paediatric Surgery at the University of Oxford from 1990 to 1996. He was Chair of Paediatric Surgery at The University of Hong Kong 1996-2922. He was the Vice- President for Research (2003-2015), was Acting President and Vice-Chancellor (February-July 2018), and was Interim Provost and Deputy Vice-Chancellor of the University of Hong Kong.(2015-March 2019) . He is currently Chair Professor and Vice-President at Macau University of Science and Technology.
Professor Tam has contributed to advances in paediatric surgery especially in the areas of minimal invasive surgery, Hirschsprungs disease and hepatobiliary diseases such as biliary atresia. He also leads a large research team in genomics and stem cell biology. He has published over 570 articles in internationally refereed journals and 30 book chapters, and is ranked amongst the top 2% of most-cited scientists in Essential Science Indicators.
Also, he serves on many international professional associations and was President of the Pacific Association of Paediatric Surgeons (2008-2009). He also serves on editorial boards of several international journals including STEM CELLS Translational Medicine, Section Editor for Developmental Biology Advances (2026-), Journal of Pediatric Surgery as the Executive Editor (till 2025) and member of International Advisory Board for the Lancet Child and Adolescent Health.. .
Professor Tam has given keynote lectures, including the Journal of Pediatric Surgery Lecture and the Suruga Lecture, at many international conferences. He is the recipient of numerous awards including the British Association of Pediatric Surgery Prize (1984), the International Outstanding Leadership Award in Endoscopy from the Ministry of Science and Technology of the Peoples Republic of China (2010), the Honorary Fellow of the American Surgical Association (2013) and the 2017 Denis Browne Gold Medal, 2020 Rehbein Medal, 2025 Coe Medal, the highest awards of the British, European and Pacific Associations of Paediatric Surgeons respectively. He was appointed the Lancet’s Series Lead for the Surgical Series of two articles and one comment on Paediatric Surgery published on 9 September 2017. He was elected Academician of the Hong Kong Academy of Sciences in 2021.
Employment
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Macau University of Science and Technology Chair Professor of Pediatric Surgery, Vice President2022 - Present
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (485)
- Immunity-metabolism-senescence axis in liver fibrosis: mechanistic insights, therapeutic targets, and translational opportunities Save
- Neonatal Kasai portoenterostomy for biliary atresia: Clinical characteristics and outcomes Save
- 4D fabrication of scaffolds facilitates the construction of cholangiocyte monolayers from human and mouse liver derived organoids Save
- iRUNNER: A Baseline Mutation Burden Regression for Identifying Gene Interaction Between Rare Variants for Diseases Save
- Identification of a 13-Gene Immune Signature in Liver Fibrosis Reveals GABRE as a Novel Candidate Biomarker Save
- Molecular Mechanisms of Fibrosis in Cholestatic Liver Diseases and Regenerative Medicine-Based Therapies Save
- Biliary atresia Save
- Environmental Toxin Biliatresone-Induced Biliary Atresia-like Abnormal Cilia and Bile Duct Cell Development of Human Liver Organoids Save
- Human liver organoid derived intra-hepatic bile duct cells support SARS-CoV-2 infection and replication Save
- Editorial commentary on Letter to Editor “Fat anchoring orchidopexy: Some concerns” and an addendum to J Pediatr Surg 2021; 56: 632–634 Save
- Human liver organoid derived intra-hepatic bile duct cells support SARS-CoV-2 infection and replication and its comparison with SARS-CoV Save
- A Comparison Between Chinese Children Infected with Coronavirus Disease-2019 and with Severe Acute Respiratory Syndrome 2003 Save
- From the editors: The COVID-19 crisis and its implications for pediatric surgeons Save
- Comparative study of the clinical characteristics and epidemiological trend of 244 COVID-19 infected children with or without GI symptoms Save
- Deletion of interleukin enhancer binding factor 2 (ILF2) resulted in defective biliary development and bile flow blockage Save
- Haematological and immunological data of Chinese children infected with coronavirus disease 2019 Save
- Laparoscopic surgical technique to enhance the management of anorectal malformations: 330 cases’ experience in a single center Save
- Quality of life and defecative function 10 years or longer after posterior sagittal anorectoplasty and laparoscopic-assisted anorectal pull-through for anorectal malformation Save
- Conditional deletion of platelet derived growth factor receptor alpha (Pdgfra) in urorectal mesenchyme causes mesenchyme apoptosis and urorectal developmental anomalies in mice Save
- Determining the optimal timing of liver transplant for pediatric patients after Kasai portoenterostomy based on disease severity scores Save