Andreas Heger

Employment

• GenomicsPLC Senior Bioinformatician
  2015 - Present
• University of Oxford CGAT Technical Director
  2013 - Present
• Medical Research Council Scientist/SeniorScientist/Technical Director
  2004 - 2013

Education

• University of Cambridge PhD
  2004 - 2008
• Technische Universität Carolo Wilhelmina zu Braunschweig Diplom Biotechnologe
  1992 - 1998

Projects & Funding

Projects & funding information is unavailable.

Publications (56)

• UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy
  Genome Research 2017 DOI: 10.1101/gr.209601.116
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• 11β-hydroxysteroid dehydrogenase-1 deficiency alters the gut microbiome response to Western diet.
  2017 DOI: 10.1530/joe-16-0578
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• Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson’s disease
  Human Molecular Genetics 2017 DOI: 10.1093/hmg/ddw412
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• Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling.
  2016 DOI: 10.1038/ismej.2016.40
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• Long noncoding RNAs in B-cell development and activation
  Blood 2016 DOI: 10.1182/blood-2015-11-680843
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• CGAT: a model for immersive personalized training in computational genomics.
  2016 DOI: 10.1093/bfgp/elv021
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• High-fat diet disrupts metabolism in two generations of rats in a parent-of-origin specific manner.
  Thomas J. G. Chambers, Michael David Morgan, Andreas Heger +2 more
  2016 DOI: 10.1038/srep31857
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• Corrigendum: Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes.
  2015 DOI: 10.1038/ncomms7814
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• Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and post-treatment prostatic biopsies from patients with advanced prostate cancer.
  2014 DOI: 10.1186/1471-2407-14-977
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• Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia.
  2014 DOI: 10.1101/gr.171645.113
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• IRF5:RelA interaction targets inflammatory genes in macrophages.
  David G. Saliba, Andreas Heger, Hayley L. Eames +11 more
  2014 DOI: 10.1016/j.celrep.2014.07.034
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• Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes.
  2014 DOI: 10.1038/ncomms4979
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• Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment.
  2014 DOI: 10.1016/j.celrep.2014.04.012
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• Sequencing depth and coverage: key considerations in genomic analyses.
  2014 DOI: 10.1038/nrg3642
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• CGAT: computational genomics analysis toolkit.
  2014
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• Pfam: the protein families database.
  2014 DOI: 10.1093/nar/gkt1223
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• GAT: a simulation framework for testing the association of genomic intervals.
  2013 DOI: 10.1093/bioinformatics/btt343
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• Next-generation Sequencing of Advanced Prostate Cancer Treated with Androgen-deprivation Therapy.
  2013 DOI: 10.1016/j.eururo.2013.08.011
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• Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates.
  2013 DOI: 10.7554/eLife.00348
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• Insights into the evolution of Darwin's finches from comparative analysis of the Geospiza magnirostris genome sequence.
  2013 DOI: 10.1186/1471-2164-14-95
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