MG
Moustafa Gabr
Weill Cornell Medicine, Stanford University
Research areas: Pharmacology, Toxicology and Pharmaceutics · Drug Discovery · Computational Drug Discovery Methods · Alzheimer's disease research and treatments · Synthesis and biological activity
0000-0001-9074-3331
Employment
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Weill Cornell Medicine Assistant Professor2022 - Present
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Stanford University Postdoc researcher2019 - 2022
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (113)
- Affinity selection-mass spectrometry discovery of small molecule ILT3 (LILRB4) binders and pharmacological characterization in Alzheimer's disease models Save
- Targeting the myeloid immune checkpoint ILT3 (LILRB4) with small molecules enables reprogramming of suppressive tumor immunity Save
- Cyclic Peptides Target CAPON and Modulate Cellular Responses under Alzheimer’s Disease-Relevant Stress Save
- Small-molecule TREM2 agonists: From artificial intelligence driven discovery to therapeutic application in Alzheimer’s disease Save
- Small Molecule Modulation of NOS1AP for Molecularly Targeted Glioblastoma Therapy Save
- Development of a high-throughput TR-FRET assay for identification of small molecule inhibitors of the LILRB4 (ILT3)-SCG2 immune checkpoint interaction Save
- Direct Small Molecule Modulation of LILRB4 (ILT3) Restores Antitumor Immunity In Vivo and in Patient-Derived Cells Save
- Phage Display-Derived Cyclic Peptides Target TREM2 and Modulate Microglial Responses Under Amyloid Stress Save
- Structure-Guided Optimization of CHI3L1 Modulators Reveals G721–0377 as a Lead Compound for Restoring Astrocyte Function in Alzheimer’s Disease Save
- HTS-Oracle X: AI-Guided Prospective Discovery of Small Molecule Immune Checkpoint Binders Save
- CAR T cell therapy beyond cancer: current status, challenges and future prospects Save
- AI-Enforced Ultra-Large Virtual Screening Discovers Potent CD28 Binders Save
- HTS-Oracle v2: Prospective Ai-Guided Discovery and Experimental Validation of Small Molecule Modulators Across Multiple Targets Save
- Discovery and optimization of small molecule inhibitors of the SLIT2/ROBO1 protein-protein interaction using DNA-encoded libraries Save
- First-in-class small molecule ROBO2 binders identified through integrated virtual screening and biophysical validation Save
- From DNA-encoded library (DEL) screening to in vivo validation: LILRB4 (ILT3)-targeted small molecules reprograms myeloid immune suppression Save
- Small molecule agonists of TREM2 reprogram microglia and protect synapses in human Alzheimer's models Save
- Exploiting NMR Ensemble Heterogeneity Enables Small Molecule Discovery against Dynamic Protein–Protein Interfaces Save
- High-Throughput CETSA Identifies Small Molecule Modulators of ILT3 (LILRB4) with Functional Activity in Human iPSC-Derived Microglia for Alzheimer’s Disease Save
- Ligandability assessment of the LAG-3 D1 domain enables discovery of a small-molecule inhibitor Save