KS
Kumar Sambamurti
Medical University of South Carolina
Research areas: Neuroscience · Cellular and Molecular Neuroscience · Alzheimer's disease research and treatments · Dementia and Cognitive Impairment Research · Neuroinflammation and Neurodegeneration Mechanisms
Employment
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Medical University of South Carolina Professor2003 - Present
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (118)
- Amyloid beta governs mitochondrial lipid metabolism defects and neurodegenerative lysosomal stress Save
- Sulfur amino acids, metabolic health and beyond: Recent advances, translational implications, and future research considerations Save
- Special Issue “Tryptophan in Nutrition and Health 3.0” Save
- Nitric Oxide as a Determinant of Human Longevity and Health Span Save
- The Lymphatic System in Neurological Disease and Alzheimer's Disease. A Brief Editorial Save
- Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease. Save
- Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer's disease. Save
- Translational inhibition of APP by Posiphen: Efficacy, pharmacodynamics, and pharmacokinetics in the APP/PS1 mouse. Save
- When figures and data contradict text: MiR346 is apparently reduced in breast cancer tissue, contrary to claims by a paper's author Save
- Meet our editorial board member Save
- Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer's disease. Save
- Beta-Amyloid Precursor Protein (βAPP) Processing in Alzheimer’s Disease (AD) and Age-Related Macular Degeneration (AMD) Save
- Preface Save
- Resolution of inflammation is altered in Alzheimer's disease Save
- Evidence for lymphatic Aβ clearance in Alzheimer's transgenic mice Save
- Evidence of a novel mechanism for partial γ-secretase inhibition induced paradoxical increase in secreted amyloid β protein. Save
- Amyloid-β precursor protein synthesis inhibitors for Alzheimer's disease treatment Save
- Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury Save
- Major carboxyl terminal fragments generated by γ-secretase processing of the Alzheimer amyloid precursor are 50 and 51 amino acids long. Save
- Synthesis of the alzheimer drug posiphen into its primary metabolic products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their inhibition of amyloid precursor protein, α-synuclein synthesis, interleukin-1β release, and cholinerg… Save