Dr S.J.S. Flora
Utah State University, Indian Institute of Toxicological Research, University of Kanpur, University of Lucknow
About
Dr. S.J.S. Flora's most highlighted contribution has been the development of new molecule engineered for therapy of chronic arsenic poisoning. Mono-isoamyl dimercaptosuccinic acid (MiADMSA) has been designed, synthesized and extensively studies by his group in not only conventional screening models but also in advanced human embryonic stem cells and derived embryoid body. The potential drug has reached the stage of ‘Investigational New Drug’ and may soon be undergoing Phase-I clinical trial in collaboration with Cadila Pharma, Ahmedabad.
He has published over 275 research papers in highly rated peer reviewed journals, including more than 50 Review article/chapters in international books, which have been widely cited (> 5000 citation) in international literature. He is Associate Editor and member editorial board of 17 prestigious international journals like Food & Chemical Toxicology (Elsevier), Journal of Trace Elements in Biology & Medicine (Elsevier), Ecotoxicology and Environmental Safety (Elsevier), Human & Experimental Toxicology, Oxidative Medicine & Cell Longevity, and Associate Editor of BMC Journal of Integrative and Alternative Medicine and Oxidant and Antioxidant in Medical Sciences etc and Guest reviewer of more than 70 international journals.
He is a Fellow of National Academy of Sciences (India) (FNASc), and was awarded prestigious Dr Kailash Nath Katju award of Madhya Pradesh Government in the year 2003 and Shakuntala Amir Chand award of Indian Council of Medical Research in 1995.
He was recently awarded prestigious DRDO Scientist of the Year Award for his contribution in developing a new drug for arsenic. He has also been conferred with prestigious ORATIONS like Prof. Govinda Achari, Prof. S.B. Pandey of Indian Pharmacological Society, Prof. R. Nath Oration of PGIMER, Chandigarh and Prof. R.C. Dalela ORATIONS of Academy of Environmental Biology. Dr Flora was also awarded Distinguished Scientist Life Time Achievement Award of Society of Toxicology (SOT, India) and Association of Biotechnology and Pharmacy (ABAP), Archana Gold medal of Academy of Environmental Biology (AEB) for his contribution in the area of Toxicology. Dr. Flora was awarded “Best New Technology Award” of Defence Research & Development Organization (DRDO) for 2009 for developing a new and the first chelating drug in India which may also be the only therapy for chronic arsenic poisoning. Dr Flora is a Board Member of International Society of Dietary Supplement and Phytomedicine (ISDSP), Rome, Italy.
Dr Flora is also Fellow of Association of Biotechnologists and Pharmacy (FABP), Academy of Environment Biology (FAEB) and Society of Science and Environment (FSSE) and a has served as executive committee member of various national and international scientific societies. He has delivered more than 200 invited lectures in India and abroad and has chaired many scientific sessions. Lastly he has supervised 25 research students for the award of PhD degree.
Employment
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Utah State University Post doctoral Research Associate1985 - 1986
Education
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Indian Institute of Toxicological Research PhD1980 - 1985
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University of Kanpur M.Sc1976 - 1978
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University of Lucknow B.S.1973 - 1975
Projects & Funding
Projects & funding information is unavailable.
Publications (232)
- Potential Epigenetic Targets for Combating Alzheimer’s Disease Save
- New Approaches in Sensing and Targeting Bacterial rRNA A-site Save
- Nanocurcumin Prevents Oxidative Stress Induced following Arsenic and Fluoride Co-exposure in Rats Save
- Nano drug delivery systems: a new paradigm for treating metal toxicity Save
- Arsenic and dichlorvos: Possible interaction between two environmental contaminants Save
- Countering effects of a combination of podophyllotoxin, podophyllotoxin β-D-glucoside and rutin hydrate in minimizing radiation induced chromosomal damage, ROS and apoptosis in human blood lymphocytes Save
- Nano drug delivery systems: a new paradigm for treating metal toxicity Save
- Combined Efficacy of Gallic Acid and MiADMSA with Limited Beneficial Effects Over MiADMSA Against Arsenic-induced Oxidative Stress in Mouse Save
- Arsenic and nicotine co-exposure lead to some synergistic effects on oxidative stress and apoptotic markers in young rat blood, liver, kidneys and brain Save
- Arsenic: Chemistry, Occurrence, and Exposure Save