SG
Simone Giovannuzzi
University of Florence, Centre National de la Recherche Scientifique
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Enzyme function and inhibition · Synthesis and biological activity · Cholinesterase and Neurodegenerative Diseases
0000-0002-0669-7481
Employment
-
University of Florence Post-doctoral Researcher2023 - Present
-
Centre National de la Recherche Scientifique Internship2022 - 2022
-
University of Florence PhD cum laude2020 - 2023
Education
-
University of Florence Pharmaceutical Chemistry and Technology2015 - 2020
Projects & Funding
Projects & funding information is unavailable.
Publications (85)
- From Identification to Enzymatic Activity Profiling: Comprehensive Characterization of BloCAβ, a Probiotic β‐Carbonic Anhydrase From Bifidobacterium longum Save
- Multitargeted Anticancer Activities: Cathepsin B–Carbonic Anhydrase IX/XII Inhibitors Show Enhanced Cytotoxicity Against Lung Adenocarcinoma Cells Save
- Discovery of Imine-Modified Quinazolinyl Sulfonamides as Dual hCA IX/XII Inhibitors with Potent Antiproliferative Activity Save
- Quantitative Competition Binding of Fluorinated Ligands by Real‐Time 19F In‐Cell NMR to Assess Isoform Selectivity in Human Cells Save
- Design and Synthesis of Bis-Triazole-Linked Benzenesulfonamides as Selective Carbonic Anhydrase IX/XII Inhibitors with Chemosensitizing Activity Save
- Discovery of a Mixed and Prodrug-Like Inhibition Mechanism for Phosphocoumarins and Phosphoquinolinones against Human Carbonic Anhydrases Save
- Coumarin–Thiourea Hybrids: Structural Features Governing CA Inhibition and Antiproliferative Effects Save
- Glycosyl Coumarins as Selective Inhibitors of Tumor-Associated Carbonic Anhydrase IX and XII: Synthesis, Structure–Activity Relationships, and Molecular Modeling Save
- First-in-Class Dual PDGFR/Carbonic Anhydrase IX/XII Inhibitors: 6,7-Dimethoxyquinoline-Sulfonamides as Promising Antileukemic Agents Save
- Targeting Metabolic and pH Regulatory Pathways in Cancer via Dual Inhibition of Nicotinamide Phosphoribosyltransferase and Carbonic Anhydrases IX and XII Save
- Sideroxylonal B: A Dimeric Phloroglucinol From Eucalyptus cinerea With In Vitro Carbonic Anhydrase Inhibition and Evaluation of Cytotoxicity and Antiviral Potential Save
- Potent carbonic anhydrase inhibition by ruthenium(II)-acetazolamide conjugates uncoupled from antiproliferative activity in vitro Save
- Harnessing coumarin privilege to achieve potency and selectivity: hypoxia-targeted alkyl coumarin-tethered phenyl quinazolinones as dual hCA IX/HSP90α inhibitors with chemosensitizing activity Save
- Correction to “Intracellular Binding of Novel Fluorinated Compounds to Carbonic Anhydrase Isoforms Explored by In-Cell 19F NMR” Save
- Tetrazole Derivatives as Multiclass Inhibitors of Bacterial Carbonic Anhydrases Save
- Intracellular Binding of Novel Fluorinated Compounds to Carbonic Anhydrase Isoforms Explored by In-Cell 19F NMR Save
- Hybrid and Chimeric Heterocycles for the Inhibition of Carbonic Anhydrases Save
- Exploring Indole-Linked Triazole Sulfonamide Derivatives as Potent Mycobacterial Carbonic Anhydrase Inhibitors: Leveraging a Tail Approach for the Design, Synthesis, and In Silico Studies─An In-Depth Multidisciplinary Study Save
- Exploration of 3‐Substituted Benzofuran‐Tethered Sulfamoyl Triazoles as Carbonic Anhydrase Inhibitors: Design, Synthesis, and Biological Evaluation Save
- Oxindole–Coumarin Hybrids With Broad‐Spectrum Anticancer Activity: Apoptosis Induction and Selective CA IX/XII Targeting Save