Anjali Hinch

Employment

• University of Oxford
• University of Oxford PI

Education

Education history is unavailable.

Projects & Funding

• The mechanism of recombination and its impacts on human mutation and disease Wellcome
  2022 - 2027

Publications (16)

• Genome-wide genealogies reveal deep admixtures forming modern humans
  2026 DOI: 10.64898/2026.04.17.719197
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• Meiotic DNA breaks drive multifaceted mutagenesis in the human germ line
  Science 2023 DOI: 10.1126/science.adh2531
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• Characterization of meiotic recombination intermediates through gene knockouts in founder hybrid mice
  Genome Research 2023 DOI: 10.1101/gr.278024.123
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• Altering the Binding Properties of PRDM9 Partially Restores Fertility across the Species Boundary.
  Molecular biology and evolution 2021 DOI: 10.1093/molbev/msab269
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• Applications of Single-Cell DNA Sequencing.
  Annual review of genomics and human genetics 2021 DOI: 10.1146/annurev-genom-111320-090436
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• ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair.
  eLife 2020 DOI: 10.7554/elife.53392
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• The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates.
  Molecular cell 2020 DOI: 10.1016/j.molcel.2020.06.015
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• Molecular structures and mechanisms of DNA break processing in mouse meiosis.
  Genes & development 2020 DOI: 10.1101/gad.336032.119
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• Molecular structures and mechanisms of DNA break processing in mouse meiosis
  2019 DOI: 10.1101/2019.12.17.876854
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• ZCWPW1 is recruited to recombination hotspots by PRDM9, and is essential for meiotic double strand break repair
  2019 DOI: 10.1101/821678
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• Factors influencing meiotic recombination revealed by whole-genome sequencing of single sperm
  Anjali Gupta Hinch, Gang Zhang, Philipp Becker +5 more
  Science 2019 DOI: 10.1126/science.aau8861
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• Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice.
  Benjamin Davies, Edouard Hatton, Nicolas Altemose +15 more
  Nature 2016 DOI: 10.1038/nature16931
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• A global reference for human genetic variation.
  Corresponding authors, Adam Auton, Gonçalo R. Abecasis +97 more
  Nature 2015 DOI: 10.1038/nature15393
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• Recombination in the human Pseudoautosomal region PAR1.
  Anjali Gupta Hinch, Nicolas Altemose, Nudrat Noor +2 more
  PLoS genetics 2014 DOI: 10.1371/journal.pgen.1004503
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• An integrated map of genetic variation from 1,092 human genomes.
  Gil McVean, Peter Donnelly, Anjali Gupta Hinch +97 more
  Nature 2012 DOI: 10.1038/nature11632
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• The landscape of recombination in African Americans.
  Anjali Gupta Hinch, Arti Tandon, Nick J. Patterson +78 more
  Nature 2011 DOI: 10.1038/nature10336
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