HK
Hiroshi Kobayashi
Tohoku University, The University of Tokyo
Research areas: Immunology and Microbiology · Immunology · T-cell and B-cell Immunology · Immunotherapy and Immune Responses · Hematopoietic Stem Cell Transplantation
0000-0002-0924-1252
Employment
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Tohoku University Associate Professor2024 - Present
Education
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The University of Tokyo Ph.D.2010 - 2014
- 2001 - 2007
Projects & Funding
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Development of a method to induce maturation of fetal hematopoietic stem cells Japan Society for the Promotion of Science2021 - 2024
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Study on the mechanism of HSC aging through quiescence maintaining culture Japan Society for the Promotion of Science2019 - 2021
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Study of aged hematopoietic stem cells through single-cell RNA-sequencing Japan Society for the Promotion of Science2017 - 2019
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Identification and characterization of biological targets of chemical expander for hematopoietic stem cells Japan Society for the Promotion of Science2016 - 2018
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Impact of hydroxylation signals on homeostatic regulation of hematopoiesis Japan Society for the Promotion of Science2015 - 2018
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ヒト造血器悪性腫瘍幹細胞の自己複製における対称性分裂・非対称分裂の役割の解明 Japan Society for the Promotion of Science2012 - 2013
Publications (42)
- Geneformer-guided multiomics integration identifies Pbx1 as a network hub of hematopoietic stem cell aging Save
- Adiponectin exerts sex-dependent effects on lipid, amino acid, and glucose metabolism during caloric restriction Save
- Decreased non-neurogenic acetylcholine in bone marrow triggers age-related defective stem/progenitor cell homing Save
- Biallelic TEDC1 variants cause a new syndrome with severe growth impairment and endocrine complications Save
- Correction: Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis Save
- SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production Save
- Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis Save
- Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis Save
- Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis and Ensures Stress Hematopoiesis Save
- Spatial heterogeneity of bone marrow endothelial cells unveils a distinct subtype in the epiphysis Save
- MBTD1 preserves adult hematopoietic stem cell pool size and function Save
- Distinct roles of the preparatory and payoff phases of glycolysis in hematopoietic stem cells Save
- Evaluating the function of murine quiescent hematopoietic stem cells following non-homologous end joining-based genome editing. Save
- The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent. Save
- Mesenchymal loss of p53 alters stem cell capacity and models human soft tissue sarcoma traits. Save
- Molecular diagnosis of 405 individuals with autism spectrum disorder. Save
- Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis and Ensures Stress Hematopoiesis Save
- A culture platform to study quiescent hematopoietic stem cells following genome editing Save
- Approaches towards Elucidating the Metabolic Program of Hematopoietic Stem/Progenitor Cells Save
- A Culture Method to Maintain Quiescent Human Hematopoietic Stem Cells. Save