Yuki Sugiura

Employment

• School of Medicine, Keio University

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (106)

• Safe lysosomal sequestration of ferrous iron is mediated via cholesterol shielding and drives senescence and ferroptosis resistance
  The EMBO Journal 2026 DOI: 10.1038/s44318-026-00939-1
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• Aberrant alternative splicing memorized in adipose tissue macrophages impedes efferocytosis during post-obesity weight loss
  Science Translational Medicine 2026 DOI: 10.1126/scitranslmed.adv0221
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• Lysophosphatidic acid drives to mirror-image pain via corpus callosum-mediated propagation of inflammatory responses
  Communications Biology 2026 DOI: 10.1038/s42003-026-10261-5
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• Inhibition of the gut ceramidase Asah2 decelerates the vertebrate ageing rate
  2026 DOI: 10.64898/2026.04.30.721799
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• Glutathione Synthesis via the Cystine/Glutamate Transporter Promotes the Formation of Tertiary Lymphoid Structures in the Kidney
  Journal of the American Society of Nephrology 2026 DOI: 10.1681/ASN.0000000825
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• M cell–dependent commensal uptake confers encephalitogenic phenotypes on γδT17 cells in Peyer’s patches
  Proceedings of the National Academy of Sciences 2026 DOI: 10.1073/pnas.2506550123
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• rW27 IgA alleviates Enterococcus faecalis-promoted CDAHFD-induced MASH in mice by attenuating the liver fibrosis
  2025 DOI: 10.21203/rs.3.rs-7472148/v1
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• Senescence-associated lysosomal dysfunction impairs cystine deprivation-induced lipid peroxidation and ferroptosis
  Nature Communications 2025 DOI: 10.1038/s41467-025-61894-9
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• Decreased non-neurogenic acetylcholine in bone marrow triggers age-related defective stem/progenitor cell homing
  Nature Communications 2025 DOI: 10.1038/s41467-025-60515-9
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• Prediction of postoperative delirium by blood metabolome analysis
  Journal of Psychiatric Research 2025 DOI: 10.1016/j.jpsychires.2025.03.028
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• Branched-chain amino acids and specific phosphatidylinositols are plasma metabolite pairs associated with menstrual pain severity
  Scientific Reports 2025 DOI: 10.1038/s41598-025-87415-8
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• Mitochondrial fatty acid oxidation drives senescence
  Science Advances 2024 DOI: 10.1126/sciadv.ado5887
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• Cholesterol sulfate prevents maternal–fetal conflict by locally modulating immune reactivity
  2024 DOI: 10.1101/2024.10.11.617779
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• Spatiotemporally distinct roles of cyclooxygenase-1 and cyclooxygenase-2 at fetomaternal interface in mice
  JCI Insight 2024 DOI: 10.1172/jci.insight.181865
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• Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies
  Paras Singh Minhas, Jeffrey R. Jones, Amira Latif‐Hernandez +30 more
  Science 2024 DOI: 10.1126/science.abm6131
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• Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis
  S. Watanuki, Hiroshi Kobayashi, Yuki Sugiura +25 more
  eLife 2024 DOI: 10.7554/eLife.87674
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• Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis
  eLife 2024 DOI: 10.7554/eLife.87674.3
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• Activation of the pentose phosphate pathway in macrophages is crucial for granuloma formation in sarcoidosis
  Journal of Clinical Investigation 2023 DOI: 10.1172/JCI171088
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• MRP1-Dependent Extracellular Release of Glutathione Induces Cardiomyocyte Ferroptosis After Ischemia-Reperfusion
  Circulation Research 2023 DOI: 10.1161/CIRCRESAHA.123.323517
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• Cellular senescence induction leads to progressive cell death via the INK4a‐RB pathway in naked mole‐rats
  The EMBO Journal 2023 DOI: 10.15252/embj.2022111133
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