Theresa Elizabeth Leon

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Publications (13)

• EZH2-Deficient T-cell Acute Lymphoblastic Leukemia Is Sensitized to CHK1 Inhibition through Enhanced Replication Stress
  Theresa E. León, Tanya Rapoz-D’Silva, Cosetta Bertoli +14 more
  Cancer Discovery 2020 DOI: 10.1158/2159-8290.CD-19-0789
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• JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia
  Marc R. Mansour, Shuning He, Zhaodong Li +24 more
  Journal of Experimental Medicine 2018 DOI: 10.1084/jem.20170484
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• Prognostic impact of the absence of biallelic deletion at the TRG locus for pediatric patients with T-cell acute lymphoblastic leukemia treated on the MRC UKALL2003 trial
  Nadine Farah, Amy A. Kirkwood, Sunniyat Rahman +11 more
  Haematologica 2018 DOI: 10.3324/haematol.2017.185801
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• APOBEC signature mutation generates an oncogenic enhancer that drives LMO1 expression in T-ALL.
  Z Li, Brian J. Abraham, Alla Berezovskaya +13 more
  Leukemia 2017 DOI: 10.1038/leu.2017.75
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• Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia.
  Sunniyat Rahman, Michael Magnussen, Theresa E. León +19 more
  Blood 2017 DOI: 10.1182/blood-2016-09-742148
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• The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism
  2017 DOI: 10.1016/j.celrep.2017.01.007
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• The nuclear receptor LXR modulates interleukin-18 levels in macrophages through multiple mechanisms
  Scientific Reports 2016 DOI: 10.1038/srep25481
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• Multiple novel regulatory mechanisms of IL-18 by the lipid-activated nuclear receptor LXR
  Atherosclerosis 2015 DOI: 10.1016/j.atherosclerosis.2015.04.044
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• Reciprocal negative cross-talk between liver X receptors (LXRs) and STAT1: effects on IFN-γ-induced inflammatory responses and LXR-dependent gene expression.
  Journal of immunology (Baltimore, Md. : 1950) 2013 DOI: 10.4049/jimmunol.1201393
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• Liver X receptors inhibit macrophage proliferation through downregulation of cyclins D1 and B1 and cyclin-dependent kinases 2 and 4.
  Journal of immunology (Baltimore, Md. : 1950) 2011 DOI: 10.4049/jimmunol.1000585
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• Molecular Biology of Rotavirus Entry and Replication
  2009 DOI: 10.1100/tsw.2009.158
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• 95-P: Role of GSTM1 and GSTT1 gene in multiple sclerosis
  Human Immunology 2008 DOI: 10.1016/j.humimm.2008.08.114
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• 100-P: Glutathione S-transferase M1 and T1 in patients with Chagas disease
  Human Immunology 2007 DOI: 10.1016/j.humimm.2007.08.123
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