Michael Magnussen

About

I am a highly-interdisciplinary research scientist with 8 years of professional laboratory-based experience in academia. I am expert in using engineering principals to interpret and modulate tissue behaviours for generating innovative human models, or perturbing animal models of development, that are multiparametric and highly biomimetic. This interdisciplinary expertise stems from my time spent in 5 UK labs working on projects covering tissue engineering, cancer biology, and in silico data mining, yet above all has been honed on bioengineering and materials science for constructing innovative in vitro and in vivo developmental and disease modelling platforms. PhD program at UCL with an unprecedented £50K consumables budget. In the 4.5 years of my PhD I combined my engineering and biomaterials expertise with knowledge of stem cell biology to generate highly biomimetic models of embryonic heart development. By the culmination of my PhD, I had exposed new roles for embryogenic geometries and ECM accumulation in myocardial patterning in the embryonic heart.

Employment

• University of Copenhagen Post Doctoral Research Associate
  2022 - Present

Education

• University College London BHF 4-year Cardiovascular Biomedicine PhD
  2017 - 2022

Projects & Funding

Projects & funding information is unavailable.

Publications (8)

• Quantifying mechanical forces during vertebrate morphogenesis
  Eirini Maniou, Silvia Todros, Anna Urciuolo +9 more
  Nature Materials 2024 DOI: 10.1038/s41563-024-01942-9
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• Hydrogel-in-hydrogel live bioprinting for guidance and control of organoids and organotypic cultures
  Anna Urciuolo, Giovanni Giuseppe Giobbe, Yixiao Dong +19 more
  Nature Communications 2023 DOI: 10.1038/s41467-023-37953-4
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• Timely delivery of cardiac mmRNAs in microfluidics enhances cardiogenic programming of human pluripotent stem cells.
  Frontiers in bioengineering and biotechnology 2022 DOI: 10.3389/fbioe.2022.871867
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• Quantifying mechanical forces during vertebrate morphogenesis
  2022 DOI: 10.21203/rs.3.rs-1095730/v1
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• Intravital three-dimensional bioprinting
  Anna Urciuolo, Ilaria Poli, Luca Brandolino +12 more
  Nature Biomedical Engineering 2020 DOI: 10.1038/s41551-020-0568-z
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• EZH2-Deficient T-cell Acute Lymphoblastic Leukemia Is Sensitized to CHK1 Inhibition through Enhanced Replication Stress.
  Theresa E. León, Tanya Rapoz-D’Silva, Cosetta Bertoli +14 more
  Cancer discovery 2020 DOI: 10.1158/2159-8290.cd-19-0789
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• Beyond Family: Modeling Non-hereditary Heart Diseases With Human Pluripotent Stem Cell-Derived Cardiomyocytes.
  Frontiers in physiology 2020 DOI: 10.3389/fphys.2020.00384
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• Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia.
  Sunniyat Rahman, Michael Magnussen, Theresa E. León +19 more
  Blood 2017 DOI: 10.1182/blood-2016-09-742148
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