AB
Amy E. Baxter
University of Pennsylvania, Children's Hospital of Philadelphia, University of Oxford, University of Cambridge, Université de Montréal
Research areas: Immunology and Microbiology · Immunology · T-cell and B-cell Immunology · HIV Research and Treatment · Cancer Immunotherapy and Biomarkers
0000-0002-1555-0713
Employment
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University of Pennsylvania Research Assistant Professor; Director of R&D2025 - Present
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Children's Hospital of Philadelphia Staff Scientist2023 - 2025
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University of Pennsylvania Post-doc2018 - 2022
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Universite de Montreal Post-doc2014 - 2018
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University of Oxford Post-doc2013 - 2014
Education
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University of Oxford D.Phil2009 - 2013
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University of Cambridge B.A. M.Sci2005 - 2009
Projects & Funding
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The role of macrophages and T-cell apoptosis/necrosis in acute HIV-1 infection and associated gastrointestinal inflammation. Wellcome Trust2009 - 2013
Publications (25)
- Self-supervised plasma proteomic representations for prospective disease prediction across varying protein availability Save
- CytoGate-Bench: an LLM benchmark for cross-panel cell gating in cytometry Save
- Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate Save
- TET2 regulates early and late transitions in exhausted CD8 + T cell differentiation and limits CAR T cell function Save
- TET2 regulates early and late transitions in exhausted CD8+T-cell differentiation and limits CAR T-cell function Save
- Efficient engineering of human and mouse primary cells using peptide-assisted genome editing Save
- In vitro modeling of CD8 + T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40 Save
- The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells Save
- Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics Save
- Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction Save
- Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function Save
- Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19 Save
- Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19 Save
- In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer Save
- Deep Immune Profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19 Save
- Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications Save
- Comprehensive mapping of immune perturbations associated with severe COVID-19 Save
- Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions Save
- Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection Save
- Multiparametric characterization of rare HIV-infected cells using an RNA-flow FISH technique. Save