Alexander Dimitri

Employment

• University of Pennsylvania Graduate Student

Education

• University of Pennsylvania PhD Candidate
  2018 - Present
• State University of New York Fredonia Bachelor of Science in Molecular Genetics
  2014 - 2018

Projects & Funding

Projects & funding information is unavailable.

Publications (9)

• TET2 regulates early and late transitions in exhausted CD8 + T cell differentiation and limits CAR T cell function
  Alexander J. Dimitri, Amy E. Baxter, Gregory M. Chen +39 more
  Science Advances 2024 DOI: 10.1126/sciadv.adp9371
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• TET2 regulates early and late transitions in exhausted CD8+T-cell differentiation and limits CAR T-cell function
  2024 DOI: 10.1101/2024.03.29.587004
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• TOX2 coordinates with TET2 to positively regulate central memory differentiation in human CAR T cells
  Science Advances 2023 DOI: 10.1126/sciadv.adh2605
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• Engineering the next-generation of CAR T-cells with CRISPR-Cas9 gene editing
  Molecular Cancer 2022 DOI: 10.1186/s12943-022-01559-z
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• BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia
  Journal of Clinical Investigation 2021 DOI: 10.1172/jci145459
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• Autologous CD4 T Lymphocytes Modified with a Tat-Dependent, Virus-Specific Endoribonuclease Gene in HIV-Infected Individuals
  Molecular Therapy 2021 DOI: 10.1016/j.ymthe.2020.11.007
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• Clinical practice: chimeric antigen receptor (CAR) T cells: a major breakthrough in the battle against cancer.
  Clinical and experimental medicine 2020 DOI: 10.1007/s10238-020-00628-1
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• Brain Organoids: Expanding Our Understanding of Human Development and Disease.
  Results and problems in cell differentiation 2018 DOI: 10.1007/978-3-319-93485-3_8
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• Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1.
  Translational psychiatry 2017 DOI: 10.1038/s41398-017-0054-x
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