RD
Rosario Diaz Gonzalez
Instituto de Parasitología y Biomedicina "López - Neyra", London School of Hygiene & Tropical Medicine, Universidad de León Facultad de Veterinaria
Research areas: Medicine · Epidemiology · Trypanosoma species research and implications · Synthesis and Characterization of Heterocyclic Compounds · Computational Drug Discovery Methods
0000-0002-3187-2704
Employment
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Instituto de Parasitología y Biomedicina López-Neyra Postdoctoral researcher2015 - Present
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London School of Hygiene and Tropical Medicine Research Fellow2013 - 2014
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Instituto de Parasitología y Biomedicina López-Neyra Postdoctoral researcher2008 - 2013
Education
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Universidad de León Facultad de Veterinaria PhD2002 - 2008
Projects & Funding
Projects & funding information is unavailable.
Publications (29)
- Pharmacophore Identification and Structure-Activity Relationship Analysis of a Series of Substituted Azaindoles as Inhibitors of Trypanosoma brucei. Save
- Establishment of a screening platform based on human coronavirus OC43 for the identification of microbial natural products with antiviral activity Save
- Strasseriolides display in vitro and in vivo activity against trypanosomal parasites and cause morphological and size defects in Trypanosoma cruzi Save
- Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes. Save
- Lead Optimization of 3,5-Disubstituted-7-Azaindoles for the Treatment of Human African Trypanosomiasis. Save
- Medicinal Chemistry Optimization of a Diaminopurine Chemotype: Toward a Lead for Trypanosoma brucei Inhibitors. Save
- Structure-property studies of an imidazoquinoline chemotype with antitrypanosomal activity. Save
- Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-b]pyridazines for the Treatment of Human African Trypanosomiasis. Save
- Hit-to-Lead Optimization of Benzoxazepinoindazoles As Human African Trypanosomiasis Therapeutics. Save
- Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents Save
- From Cells to Mice to Target: Characterization of NEU-1053 (SB-443342) and Its Analogues for Treatment of Human African Trypanosomiasis Save
- Novel 1,2-dihydroquinazolin-2-ones: Design, synthesis, and biological evaluation against Trypanosoma brucei Save
- A Replicative In Vitro Assay for Drug Discovery against Leishmania donovani Save
- Identification of "preferred" Human Kinase Inhibitors for Sleeping Sickness Lead Discovery. Are Some Kinases Better than Others for Inhibitor Repurposing? Save
- Establishment of a structure-activity relationship of 1 H-imidazo[4,5-c]quinoline-based kinase inhibitor NVP-BEZ235 as a lead for African sleeping sickness Save
- Identification and Characterization of Hundreds of Potent and Selective Inhibitors of Trypanosoma brucei Growth from a Kinase-Targeted Library Screening Campaign Save
- Identification and characterization of the regions involved in the nuclear translocation of the heterodimeric leishmanial DNA topoisomerase IB. Save
- Target of rapamycin (TOR) kinase in Trypanosoma brucei: An extended family Save
- A pentapeptide signature motif plays a pivotal role in Leishmania DNA topoisomerase IB activity and camptothecin sensitivity Save
- Diamine and aminoalcohol derivatives active against Trypanosoma brucei Save