Chi Fung Joseph Ng

Employment

• University College London Research Fellow
  2022 - Present
• King's College London
  ? - 2022

Education

• King's College London PhD
  2016 - 2020
• University of Hong Kong
  2012 - 2016

Projects & Funding

Projects & funding information is unavailable.

Publications (34)

• Tuning antibody stability and function by rational designs of framework mutations
  Joseph Chi-Fung Ng, Alicia M. Chenoweth, Maria Laura De Sciscio +12 more
  Mabs 2025 DOI: 10.1080/19420862.2025.2532117
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• Tuning antibody stability and function by rational designs of framework mutations
  2025 DOI: 10.1101/2025.03.13.642419
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• ImmunoMatch learns and predicts cognate pairing of heavy and light immunoglobulin chains
  2025 DOI: 10.1101/2025.02.11.637677
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• IFN-γ-dependent regulation of intestinal epithelial homeostasis by NKT cells
  Cell Reports 2024 DOI: 10.1016/j.celrep.2024.114948
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• Clinical research in endometrial cancer
  Carien L. Creutzberg, Jae‐Weon Kim, Gemma Eminowicz +93 more
  The Lancet. Oncology 2024 DOI: 10.1016/S1470-2045(24)00192-X
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• VCAb: a web-tool for structure-guided exploration of antibodies.
  Bioinformatics advances 2024 DOI: 10.1093/bioadv/vbae137
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• Predicting class switch recombination in B-cells from antibody repertoire data.
  Biometrical journal. Biometrische Zeitschrift 2024 DOI: 10.1002/bimj.202300171
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• VCAb: A web-tool for structure-guided antibody engineering
  2024 DOI: 10.1101/2024.06.05.597540
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• TITINdb2 – Expanding Annotation and Structural Information for Protein Variants in the Giant Sarcomeric Protein Titin
  2024 DOI: 10.1101/2024.05.08.593166
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• Thioredoxin is a metabolic rheostat controlling regulatory B cells.
  Nature immunology 2024 DOI: 10.1038/s41590-024-01798-w
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• Modelling the assembly and flexibility of antibody structures.
  Current opinion in structural biology 2023 DOI: 10.1016/j.sbi.2023.102757
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• in-silico and in-vitro analysis of IL36RN mutations reveals critical residues for the function of the interleukin-36 receptor complex
  Journal of Investigative Dermatology 2023 DOI: 10.1016/j.jid.2023.06.191
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• sciCSR infers B cell state transition and predicts class-switch recombination dynamics using single-cell transcriptomic data.
  Nature methods 2023 DOI: 10.1038/s41592-023-02060-1
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• B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma
  Silvia Crescioli, Isabel Corrêa, Joseph Chi-Fung Ng +40 more
  Nature Communications 2023 DOI: 10.1038/s41467-023-39042-y
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• sciCSR infers B cell state transition and predicts class-switch recombination dynamics using single-cell transcriptomic data
  2023 DOI: 10.1101/2023.02.02.526789
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• Diversification of immunoglobulin genes by gene conversion in the domestic chicken (Gallus gallus domesticus).
  Discovery immunology 2023 DOI: 10.1093/discim/kyad002
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• Chickens, more than humans, focus the diversity of their immunoglobulin genes on the complementarity-determining region but utilise amino acids, indicative of a more cross-reactive antibody repertoire.
  Frontiers in immunology 2022 DOI: 10.3389/fimmu.2022.837246
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• Pandemic, Epidemic, Endemic: B Cell Repertoire Analysis Reveals Unique Anti-Viral Responses to SARS-CoV-2, Ebola and Respiratory Syncytial Virus.
  Frontiers in immunology 2022 DOI: 10.3389/fimmu.2022.807104
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• Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes In Triple-Negative Breast Cancer
  Cancer Research 2021 DOI: 10.1158/0008-5472.CAN-20-3773
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• Pandemic, epidemic, endemic: B cell repertoire analysis reveals unique anti-viral responses to SARS-CoV-2, Ebola and Respiratory Syncytial Virus
  2021 DOI: 10.1101/2021.08.19.456951
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