Sean Warren

Employment

• Garvan Institute of Medical Research Research Officer
  2015 - Present
• Imperial College London

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (34)

• Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse
  Science Advances 2023 DOI: 10.1126/sciadv.adf9063
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• Shedding new light on RhoA signalling as a drug target in vivo using a novel RhoA-FRET biosensor mouse
  Small GTPases 2020 DOI: 10.1080/21541248.2018.1438024
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• Fluids and their mechanics in tumour transit: shaping metastasis
  Nature Reviews Cancer 2020 DOI: 10.1038/s41568-019-0221-x
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• CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan
  Claire Vennin, Pauline Mélénec, Romain Rouet +97 more
  Nature Communications 2019 DOI: 10.1038/s41467-019-10968-6
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• Removing physiological motion from intravital and clinical functional imaging data
  eLife 2018 DOI: 10.7554/eLife.35800
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• Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology
  Scientific Reports 2017 DOI: 10.1038/s41598-017-17177-5
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• Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis
  Claire Vennin, Venessa T. Chin, Sean C. Warren +49 more
  Science Translational Medicine 2017 DOI: 10.1126/scitranslmed.aai8504
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• Characterisation of new gated optical image intensifiers for fluorescence lifetime imaging
  Review of Scientific Instruments 2017 DOI: 10.1063/1.4973917
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• Imaging of Metabolic Status in 3D Cultures with an Improved AMPK FRET Biosensor for FLIM
  Sensors 2016 DOI: 10.3390/s16081312
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• Visualising apoptosis in live zebrafish using fluorescence lifetime imaging with optical projection tomography to map FRET biosensor activity in space and time.
  2016
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• Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue.
  2016
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• Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1.
  2016
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• Adaptive Multiphoton Endomicroscope Incorporating a Polarization-Maintaining Multicore Optical Fibre
  Ieee Journal of Selected Topics in Quantum Electronics 2016 DOI: 10.1109/JSTQE.2015.2488283
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• Recruitment Kinetics of Tropomyosin Tpm3.1 to Actin Filament Bundles in the Cytoskeleton Is Independent of Actin Filament Kinetics
  Plos One 2016 DOI: 10.1371/journal.pone.0168203
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• Screening for protein-protein interactions using Forster resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM).
  2016
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• A flexible wide-field FLIM endoscope utilising blue excitation light for label-free contrast of tissue
  Journal of Biophotonics 2015 DOI: 10.1002/jbio.201300203
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• Automated multiwell fluorescence lifetime imaging for Forster resonance energy transfer assays and high content analysis
  Analytical Methods 2015 DOI: 10.1039/c5ay00244c
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• Correction Approach for Delta Function Convolution Model Fitting of Fluorescence Decay Data in the Case of a Monoexponential Reference Fluorophore
  Journal of Fluorescence 2015 DOI: 10.1007/s10895-015-1583-4
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• Fibre-coupled multiphoton microscope with adaptive motion compensation
  Biomedical Optics Express 2015 DOI: 10.1364/BOE.6.001876
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• Homo-FRET Based Biosensors and Their Application to Multiplexed Imaging of Signalling Events in Live Cells.
  2015
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