Lais Cristina G F Palhares

Employment

• Manchester Cancer Research Centre Technical Specialist - ACED
  2025 - Present
• King's College London Postdoctoral Research Associate
  2021 - 2024

Education

• University of Liverpool Doctorate degree
  2018 - 2019
• Federal University of Rio Grande do Norte PhD
  2016 - 2019

Projects & Funding

Projects & funding information is unavailable.

Publications (18)

• Hybrid IgE-IgG1 antibodies (IgEG): a new antibody class that combines IgE and IgG functionality
  mAbs 2025 DOI: 10.1080/19420862.2025.2502673
  +Save
• Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interaction
  Gabriel Osborn, Jacobo López‐Abente, Rebecca Adams +25 more
  Nature Communications 2025 DOI: 10.1038/s41467-025-57870-y
  +Save
• Fc-mediated immune stimulating, pro-inflammatory and antitumor effects of anti-HER2 IgE against HER2-expressing and trastuzumab-resistant tumors
  Melanie Grandits, Lais C. G. F. Palhares, Gabriel Osborn +15 more
  Journal for ImmunoTherapy of Cancer 2025 DOI: 10.1136/jitc-2024-010945
  +Save
• An IgE antibody targeting HER2 identified by clonal selection restricts breast cancer growth via immune-stimulating activities
  Lais C. G. F. Palhares, Melanie Grandits, Katie Stoker +11 more
  Journal of Experimental & Clinical Cancer Research 2025 DOI: 10.1186/s13046-025-03319-5
  +Save
• IgE glycosylation and impact on structure and function: A systematic review
  Allergy 2024 DOI: 10.1111/all.16259
  +Save
• Chondroitin Sulfate Proteoglycan 4 (CSPG4) as an Emerging Target for Immunotherapy to Treat Melanoma
  Xinyi Chen, Shabana Habib, Madalina Alexandru +17 more
  Cancers 2024 DOI: 10.3390/cancers16193260
  +Save
• Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4
  Jitesh Chauhan, Melanie Grandits, Lais C. G. F. Palhares +37 more
  Nature Communications 2023 DOI: 10.1038/s41467-023-37811-3
  +Save
• Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes
  Heather J. Bax, Jitesh Chauhan, Chara Stavraka +33 more
  British Journal of Cancer 2023 DOI: 10.1038/s41416-022-02031-x
  +Save
• Clinical and Translational Significance of Basophils in Patients with Cancer
  Jitesh Chauhan, Chara Stavraka, Melanie Grandits +6 more
  Cells 2022 DOI: 10.3390/cells11030438
  +Save
• Chemical Modification of Glycosaminoglycan Polysaccharides
  Molecules 2021 DOI: 10.3390/molecules26175211
  +Save
• In Vitro Antitumor Potential of Sulfated Polysaccharides from Seaweed Caulerpa cupressoides var. flabellata
  Marine Biotechnology 2021 DOI: 10.1007/s10126-020-10004-5
  +Save
• In vitro antitumor and anti-angiogenic activities of a shrimp chondroitin sulfate
  International Journal of Biological Macromolecules 2020 DOI: 10.1016/j.ijbiomac.2020.06.100
  +Save
• A further unique chondroitin sulfate from the shrimp Litopenaeus vannamei with antithrombin activity that modulates acute inflammation
  Carbohydrate Polymers 2019 DOI: 10.1016/j.carbpol.2019.115031
  +Save
• 2,3-Di-O-sulfo glucuronic acid: An unmodified and unusual residue in a highly sulfated chondroitin sulfate from Litopenaeus vannamei
  Carbohydrate Polymers 2018 DOI: 10.1016/j.carbpol.2017.12.018
  +Save
• Anti-IIa activity and antitumor properties of a hybrid heparin/heparan sulfate-like compound from Litopenaeus vannamei shrimp
  International Journal of Biological Macromolecules 2018 DOI: 10.1016/j.ijbiomac.2018.06.143
  +Save
• Structural characterization of blackberry wine polysaccharides and immunomodulatory effects on LPS-activated RAW 264.7 macrophages
  Food Chemistry 2018 DOI: 10.1016/j.foodchem.2018.02.122
  +Save
• Structural characterization of polysaccharides from Cabernet Franc, Cabernet Sauvignon and Sauvignon Blanc wines: Anti-inflammatory activity in LPS stimulated RAW 264.7 cells
  Carbohydrate Polymers 2018 DOI: 10.1016/j.carbpol.2017.12.082
  +Save
• A non-hemorrhagic hybrid heparin/heparan sulfate with anticoagulant potential
  Carbohydrate Polymers 2014 DOI: 10.1016/j.carbpol.2013.08.063
  +Save