Dr. RAMKUMAR MODUKURI
Also known as: RMODUKURI, RAM K. MODUKURI
Baylor College of Medicine, California Institute for Biomedical Research, Central Drug Research Institute, Acharya Nagarjuna University
Research areas: Chemistry · Organic Chemistry · Synthesis and biological activity · Bone Metabolism and Diseases · Synthesis and Characterization of Heterocyclic Compounds
0000-0002-5849-4088
About
I am Ramkumar Modukuri, presently I am working as post-doctoral position in department of Medicinal Chemistry at California Institute For Biomedical Research (Calibr), San Diego. I have completed my Ph.D. in field of Synthetic and Medicinal Chemistry from CSIR- Central Drug Research Institute, Lucknow-India.
Currently in my post doctorate, I am working to ‘‘Host-targeted therapies for Diarrheal disease: Novel approaches to identifying anti-cryptosporidium drugs’’. I am also engaged in different projects in present institute. During my Ph.D. research, I have gained experience in Medicinal Chemistry, During in my research, I have designed and synthesized medicinally active different types of oxygen heterocycles as privileged structures to evaluate their various pharmaceutical properties like anti-alzheimer’s, anti-parkinson’s, anti-depressant, anti-osteoporotic, anti-malarial and anti-filarial activities. In this process, I have synthesized a large number of different heterocyclic compounds of pharmacological interest. More interestingly, I have designed different chemical entities in which can interact with particular cite of action. I have experience in designing and synthesis of medicinally active hit to lead optimization of lead active scaffolds. My research work has been published in international journals of repute 15 International papers, details of which are being attached with the CV.
My citations indices are available at
http://scholar.google.co.in/citations?user=aoEPqxAAA AAJ&hl=en
The research work has been published through peer reviewed publications. Two of my works have accepted as a front cover art in ACS Medicinal Chemistry Letters (2014 & 2015).
Employment
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Baylor College of Medicine Staff Scientist2019 - Present
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California Institute for Biomedical Research Postdoc Fellow2015 - 2019
Education
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California Institute for Biomedical Research Postdoctoral Fellow2015 - Present
- 2009 - 2015
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Acharya Nagarjuna University M.Sc (Organic Chemistry)2006 - 2008
Projects & Funding
Projects & funding information is unavailable.
Publications (20)
- Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening Save
- Synthesis of Highly Substituted Imidazo[1,5-a]quinoxalines Through a Multicomponent Reaction Followed by Deprotection-Cyclization Save
- ChemInform Abstract: Synthesis of Highly Substituted Imidazo[1,5-a]quinoxalines Through a Multicomponent Reaction Followed by Deprotection-Cyclization. Save
- Development of Leishmania donovani stably expressing DsRed for flow cytometry-based drug screening using chalcone thiazolyl-hydrazone as a new antileishmanial target Save
- Hybrids of coumarin–indole: design, synthesis and biological evaluation in Triton WR-1339 and high-fat diet induced hyperlipidemic rat models Save
- Novel Chalcone–Thiazole Hybrids as Potent Inhibitors of Drug ResistantStaphylococcus aureus Save
- ChemInform Abstract: Benzofuran-Chalcone Hybrids as Potential Multifunctional Agents Against Alzheimer′s Disease: Synthesis and in vivo Studies with Transgenic Caenorhabditis elegans. Save
- Design and synthesis of new series of coumarin–aminopyran derivatives possessing potential anti-depressant-like activity Save
- Discovery of 3-Arylcoumarin-tetracyclic Tacrine Hybrids as Multifunctional Agents against Parkinson’s Disease Save
- Synthesis and evaluation of new 3-phenylcoumarin derivatives as potential antidepressant agents Save
- Benzofuran-Chalcone Hybrids as Potential Multifunctional Agents against Alzheimer’s Disease: Synthesis and in vivo Studies with TransgenicCaenorhabditis elegans Save
- Synthesis and antifilarial activity of chalcone–thiazole derivatives against a human lymphatic filarial parasite, Brugia malayi Save
- ChemInform Abstract: Advances in Drug Design and Discovery. Part 25. Hybrid Benzofuran-Bisindole Derivatives: New Prototypes with Promising Antihyperlipidemic Activities. Save
- Hybrid benzofuran–bisindole derivatives: New prototypes with promising anti-hyperlipidemic activities Save
- Discovery of Coumarin–Dihydropyridine Hybrids as Bone Anabolic Agents Save
- Synthesis and evaluation of new coumarin–pyridine hybrids with promising anti-osteoporotic activities Save
- Antiplasmodial activity of novel keto-enamine chalcone-chloroquine based hybrid pharmacophores Save
- Discovery and synthesis of novel substituted benzocoumarins as orally active lipid modulating agents Save
- Synthesis and anti-inflammatory activity of novel biscoumarin–chalcone hybrids Save
- ChemInform Abstract: Advances in Drug Design and Discovery. Part 11. Synthesis and Antiinflammatory Activity of Novel Biscoumarin-Chalcone Hybrids. Save