Anna Maria Porcelli
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Mitochondrial Function and Pathology · Cancer, Hypoxia, and Metabolism · Ovarian cancer diagnosis and treatment
0000-0002-6209-0692
About
Anna Maria Porcelli is Associate Professor at the Department of Pharmacy and Biotechnology, University of Bologna. She conducts her research in the field of cellular biochemistry with particular interest for the role of mitochondria and mitochondrial DNA in the metabolic and hypoxic adaptation during the different stages of tumor progression. In the recent years her research has focused on the role of complex I of oxidative phosphorylation as a modulator of the tumorigenic potential in vitro and in vivo models. Involved in national and international research projects, she collaborates with several European Institutes. Since 2012 she has been a member of CIRI - Life Sciences and Technologies for Health at University of Bologna. Author of numerous publications in peer-reviewed journals, she has been bestowed with several scientific awards.
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Publications (131)
- Combining circulating tumor cell and circulating cell-free DNA analyses broadens clinical applicability of liquid biopsy in high grade serous tubo-ovarian carcinoma Save
- Somatic pathogenic mitochondrial DNA mutations independently predict worse prognosis in hepatocellular carcinoma Save
- Clinically Informed Intelligent Classification of Ovarian Cancer Cells by Label-Free Holographic Imaging Flow Cytometry Save
- Immunomagnetic enrichment coupled to PAX8/TP53 molecular pathology approach increases sensitivity in the detection of ovarian cancer cells in ascites Save
- Mitochondrial chaperonin DNAJC15 promotes vulnerability to ferroptosis of chemoresistant ovarian cancer cells Save
- Perfusion-based ex vivo culture of frozen ovarian cancer tissues with preserved tumor microenvironment Save
- AI is a viable alternative to high throughput screening: a 318-target study Save
- Biochemical and computational approaches to dissect the effect of MT-CYB pathogenic mutations on respiratory chain activity and assembly Save
- Downregulation of PLIN2 in human dermal fibroblasts impairs mitochondrial function in an age-dependent fashion and induces cell senescence via GDF15 Save
- Ketone bodies resume mitochondrial respiration in neuronal progenitors from iPSCs of patients with AGC1 deficiency Save
- Label-free identification of T-lymphocytes in holographic microscopy empowered by machine learning Save
- Mitochondrial Chaperonin MCJ Promotes Vulnerability to Ferroptosis of Chemoresistant Ovarian Cancer Cells – Dataset Save
- Optimizing label free circulating tumor cell detection for liquid biopsy in ovarian cancer Save
- Pathogenic mitochondrial DNA variants are associated with response to anti-VEGF therapy in ovarian cancer PDX models Save
- Respiratory complex I deficiency triggers OMA1-mediated integrated stress response and affects lipid homeostasis during glucose restriction Save
- Strategies of T-Cells Identification in AI-Powered Quantitative Phase Imaging Flow Cytometry Save
- Label-free liquid biopsy through the identification of tumor cells by machine learning-powered tomographic phase imaging flow cytometry Save
- Microstructured soft devices for the growth and analysis of populations of homogenous multicellular tumor spheroids Save
- Editorial: Mitochondria as a hub in cellular signaling Save
- Glucocorticoid receptor antagonization propels endogenous cardiomyocyte proliferation and cardiac regeneration Save