Palak Patel

About

I am a protein biochemist with expertise in structural biology, protein design and
engineering, and biophysics. My current research focuses on understanding the mechanisms
for productive antibody neutralization of malaria parasites, identify neutralizing-antibody
epitopes, and ultimately the structure-guided design of immunogens for vaccine
development.

Employment

• National Institute of Allergy and Infectious Diseases Postdoctoral fellow
  2019 - Present
• Mynvax Pvt. Ltd. Scientist
  2017 - 2019

Education

• Nirma University PhD
  2011 - 2018

Projects & Funding

Projects & funding information is unavailable.

Publications (12)

• A Plasmodium-derived nanoparticle vaccine elicits sterile protection against malaria in mice
  Nature Microbiology 2025 DOI: 10.1038/s41564-025-02209-y
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• Structure-based design of a strain transcending AMA1-RON2L malaria vaccine
  Palak N. Patel, Thayne H. Dickey, Ababacar Diouf +7 more
  Nature Communications 2023 DOI: 10.1038/s41467-023-40878-7
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• Structural vaccinology of malaria transmission-blocking vaccines.
  Expert review of vaccines 2021 DOI: 10.1080/14760584.2021.1873135
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• Synthesis of 2-,4,-6-, and/or 7-substituted quinoline derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors and anticancer agents: 3D QSAR-assisted design.
  Vivek K. Vyas, Gulamnizami Qureshi, Drashti Oza +4 more
  Bioorganic & medicinal chemistry letters 2019 DOI: 10.1016/j.bmcl.2019.01.038
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• Inhibition of amyloid fibril formation of lysozyme by ascorbic acid and a probable mechanism of action.
  Palak N. Patel, Krupali Parmar, Dhaval Patel

  +3 more

  • Suresh Kumar
  • Manan Trivedi
  • Mili Das
  International journal of biological macromolecules 2018 DOI: 10.1016/j.ijbiomac.2018.03.152
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• Inhibition of insulin amyloid fibrillation by Morin hydrate.
  Palak N. Patel, Krupali Parmar, Mili Das
  International journal of biological macromolecules 2017 DOI: 10.1016/j.ijbiomac.2017.11.168
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• Combined in silico approaches for the identification of novel inhibitors of human islet amyloid polypeptide (hIAPP) fibrillation.
  Palak N. Patel, Krupali Parmar, Vivek K. Vyas +2 more
  Journal of molecular graphics & modelling 2017 DOI: 10.1016/j.jmgm.2017.09.004
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• Titanium dioxide nanoparticles: an in vitro study of DNA binding, chromosome aberration assay, and comet assay.
  Suhani Patel, Palak N. Patel, Sonal Rajiv Bakshi
  Cytotechnology 2017 DOI: 10.1007/s10616-016-0054-3
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• Molecular modeling study for the design of novel acetyl-CoA carboxylase inhibitors using 3D QSAR, molecular docking and dynamic simulations.
  Vivek K. Vyas, Mohini Dabasia, Gulamnizami Qureshi +2 more
  Journal of biomolecular structure & dynamics 2016 DOI: 10.1080/07391102.2016.1204945
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• Synthesis, anti-inflammatory, analgesic, 5-lipoxygenase (5-LOX) inhibition activities, and molecular docking study of 7-substituted coumarin derivatives.
  Pavan Srivastava, Vivek K. Vyas, Bhavesh C. Variya +3 more
  Bioorganic chemistry 2016 DOI: 10.1016/j.bioorg.2016.06.004
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• DNA binding and dispersion activities of titanium dioxide nanoparticles with UV/vis spectrophotometry, fluorescence spectroscopy and physicochemical analysis at physiological temperature
  Suhani Patel, Palak N. Patel, Sachin B. Undre

  +3 more

  • Shivani R. Pandya
  • Man Singh
  • Sonal Rajiv Bakshi
  Journal of Molecular Liquids 2016 DOI: 10.1016/j.molliq.2015.11.002
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• Ligand and structure-based approaches for the identification of SIRT1 activators.
  Vivek K. Vyas, Ashutosh Goel, Manjunath D. Ghate +1 more
  Chemico-biological interactions 2015 DOI: 10.1016/j.cbi.2015.01.001
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