LS
Leandro R. Soria
Telethon Institute of Genetics and Medicine-TIGEM, National University of Rosario
Research areas: Biochemistry, Genetics and Molecular Biology · Biochemistry · Amino Acid Enzymes and Metabolism · Ion Transport and Channel Regulation · Metabolism and Genetic Disorders
0000-0002-7124-856X
Employment
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Telethon Institute of Genetics and Medicine-TIGEM Post-Doc2014 - Present
Education
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Universidad Nacional de Rosario PhD in Biological Sciences2006 - 2012
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Universidad Nacional de Rosario MSc in Biotechnology2000 - 2005
Projects & Funding
Projects & funding information is unavailable.
Publications (23)
- S-Nitrosylation of glycogen phosphorylase regulates nuclear glycogenolysis and is impaired in metabolic liver disorders. Save
- Author Correction: ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response Save
- ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response Save
- O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis Save
- Beclin‐1‐mediated activation of autophagy improves proximal and distal urea cycle disorders Save
- Progress and challenges in development of new therapies for urea cycle disorders. Save
- Hepatic glutamine synthetase augmentation enhances ammonia detoxification. Save
- Ammonia and autophagy: An emerging relationship with implications for disorders with hyperammonemia. Save
- Targeting autophagy for therapy of hyperammonemia. Save
- Enhancement of hepatic autophagy increases ureagenesis and protects against hyperammonemia. Save
- Down-regulation of hepatocyte nuclear factor-4α and defective zonation in livers expressing mutant Z α1-antitrypsin. Save
- Hepatic gene transfer of human aquaporin-1 improves bile salt secretory failure in rats with estrogen-induced cholestasis. Save
- Acidosis-induced downregulation of hepatocyte mitochondrial aquaporin-8 and ureagenesis from ammonia. Save
- Adenoviral transfer of human aquaporin-1 gene to rat liver improves bile flow in estrogen-induced cholestasis. Save
- Lipopolysaccharide impairs hepatocyte ureagenesis from ammonia: involvement of mitochondrial aquaporin-8. Save
- Endothelin-1 and -3 induce choleresis in the rat through ETB receptors coupled to nitric oxide and vagovagal reflexes. Save
- Ammonia detoxification via ureagenesis in rat hepatocytes involves mitochondrial aquaporin-8 channels. Save
- Hepatocyte aquaporins in bile formation and cholestasis. Save
- Aquaporin-8-facilitated mitochondrial ammonia transport. Save
- Glucagon induces the gene expression of aquaporin-8 but not that of aquaporin-9 water channels in the rat hepatocyte. Save