SG
Sonam Gurung
University College London, University of Bristol
Research areas: Biochemistry, Genetics and Molecular Biology · Clinical Biochemistry · Metabolism and Genetic Disorders · RNA Interference and Gene Delivery · Neuroscience and Neuropharmacology Research
0000-0003-3271-5273
Employment
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University College London Postdoctoral Fellow2019 - Present
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University of Bristol Postdoctoral Researcher2018 - 2019
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University of Bristol PhD student2014 - 2018
Education
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University of Bristol Biochemistry with Year In Industry2010 - 2014
Projects & Funding
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Investigating synaptic implications of Kainate Receptor RNA editing. Elizabeth Blackwell Institute2018 - 2019
Publications (22)
- S-Nitrosylation of glycogen phosphorylase regulates nuclear glycogenolysis and is impaired in metabolic liver disorders. Save
- Safety and efficacy analysis of in vivo lentiviral gene therapy in pre-clinical ARC syndrome models Save
- Delivering the Message: Translating <scp>mRNA</scp> Therapy for Liver Inherited Metabolic Diseases Save
- Macrophage Inhibitor Clodronate Enhances Liver Transduction of Lentiviral but Not Adeno-Associated Viral Vectors or mRNA Lipid Nanoparticles in Neonatal and Juvenile Mice Save
- Optimized and Simplified Technique for the Production and Culture of Precision-Cut Liver Slices Save
- The incidence of movement disorder increases with age and contrasts with subtle and limited neuroimaging abnormalities in argininosuccinic aciduria Save
- Ex vivo precision-cut liver slices model disease phenotype and monitor therapeutic response for liver monogenic diseases Save
- mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria Save
- Ex vivo precision-cut liver slices model disease phenotype and monitor therapeutic response for liver monogenic diseases Save
- The exosome journey: from biogenesis to uptake and intracellular signalling. Save
- Clinical applications for exosomes: are we there yet? Save
- Beclin‐1‐mediated activation of autophagy improves proximal and distal urea cycle disorders Save
- Beclin-1-mediated activation of autophagy improves proximal and distal urea cycle disorders Save
- Gene therapy for inherited metabolic diseases. Save
- 2020 ASGCT Annual Meeting Abstracts Save
- Ephrin/Eph receptor interaction facilitates macrophage recognition of differentiating human erythroblasts Save
- Changes in excitatory and inhibitory receptor expression and network activity during induction and establishment of epilepsy in the rat Reduced Intensity Status Epilepticus (RISE) model Save
- Exciting Times: New Advances Towards Understanding the Regulation and Roles of Kainate Receptors Save
- ADAR2-mediated Q/R editing of GluK2 regulates kainate receptor upscaling in response to suppression of synaptic activity Save
- Assembly, Secretory Pathway Trafficking, and Surface Delivery of Kainate Receptors Is Regulated by Neuronal Activity Save