James Allan

Employment

• Newcastle University Professor of Cancer Genetics
  2007 - Present
• Newcastle University Professor of Cancer Genetics
  2007 - Present

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (109)

• Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation
  Science 2026 DOI: 10.1126/science.adx4174
  +Save
• Mendelian randomization of immune cell phenotypes to discover potential drug targets for B-cell malignancy
  Blood Cancer Journal 2025 DOI: 10.1038/s41408-025-01277-x
  +Save
• Landscape of TET2 Mutations: From Hematological Malignancies to Solid Tumors
  Cancer Medicine 2025 DOI: 10.1002/cam4.70792
  +Save
• Biallelic TET2 mutations confer sensitivity to 5'-azacitidine in acute myeloid leukemia.
  JCI insight 2023 DOI: 10.1172/jci.insight.150368
  +Save
• Inherited cancer predisposing mutations in patients with therapy-related myeloid neoplasms.
  British journal of haematology 2022 DOI: 10.1111/bjh.18543
  +Save
• Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features.
  Nature genetics 2022 DOI: 10.1038/s41588-022-01211-y
  +Save
• Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia.
  Blood 2022 DOI: 10.1182/blood.2021015036
  +Save
• A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
  Journal of medicinal chemistry 2022 DOI: 10.1021/acs.jmedchem.2c00671
  +Save
• hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia.
  Cell reports. Medicine 2022 DOI: 10.1016/j.xcrm.2022.100717
  +Save
• Genome-wide association study identifies susceptibility loci for acute myeloid leukemia.
  Nature communications 2021 DOI: 10.1038/s41467-021-26551-x
  +Save
• Genome-Wide Association Analyses Identify Variants in IRF4 Associated With Acute Myeloid Leukemia and Myelodysplastic Syndrome Susceptibility.
  Frontiers in genetics 2021 DOI: 10.3389/fgene.2021.554948
  +Save
• Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia.
  Nature communications 2021 DOI: 10.1038/s41467-020-20822-9
  +Save
• Genetic susceptibility to breast cancer in lymphoma survivors
  Blood 2019 DOI: 10.1182/blood-2019-01-894279
  +Save
• Erratum to: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (Nature Communications, (2018), 9, 1, (1340), 10.1038/s41467-018-03178-z)
  Nature Communications 2019 DOI: 10.1038/s41467-018-08106-9
  +Save
• Erratum: The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation (Cancer Cell (2018) 34(4) (626–642.e8)(S1535610818303751)(10.1016/j.ccell.2018.08.015))
  Cancer Cell 2019 DOI: 10.1016/j.ccell.2019.03.012
  +Save
• Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology
  Blood Cancer Journal 2019 DOI: 10.1038/s41408-018-0162-8
  +Save
• Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk
  Nature Communications 2019 DOI: 10.1038/s41467-019-13069-6
  +Save
• Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics
  Nature Communications 2019 DOI: 10.1038/s41467-019-11582-2
  +Save
• Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
  Amand Floriaan Schmidt, Michael Vaclav Holmes, David Preiss +97 more
  BMC Cardiovascular Disorders 2019 DOI: 10.1186/s12872-019-1187-z
  +Save
• Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia
  Jayaram Vijayakrishnan, James B. Studd, Peter Broderick +92 more
  Nature Communications 2018 DOI: 10.1038/s41467-018-03178-z
  +Save