Roshan Katekar
Central Drug Research Institute, Government College of Pharmacy Karad, Shree Santkrupa College of Pharmacy
Research areas: Pharmacology, Toxicology and Pharmaceutics · Drug Discovery · Computational Drug Discovery Methods · Drug Solubulity and Delivery Systems · HIV Research and Treatment
0000-0003-1374-0828
About
Specialized in analytical and bio-analytical method development and validation of small molecules, natural compounds, extracts and protein therapeutics according to regulatory guidelines. Pharmacokinetic background will help in design of pharmacokinetic studies, drug metabolism-pharmacokinetics (DMPK) studies, pharmacokinetic-pharmacodynamic (PK-PD) studies. I also interested in nanomaterial based targeted delivery to tissue of interest through development of layer by layer technology, nano-crystal, solid-lipid nanoparticles, and ligand based targeting. Focus on product development: pre-formulation, formulation and pre-clinical evaluation of dosage forms.
Employment
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Central Drug Research Institute Senior Research Fellow2019 - 2022
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Central Drug Research Institute Project-Junior Research Fellow2018 - 2019
Education
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Central Drug Research Institute Doctor of Philosophy (PhD)2019 - 2023
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Government College of Pharmacy Karad Master of Pharmacy2015 - 2017
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Shree Santkrupa College of Pharmacy Bachelor of Pharmacy2011 - 2015
Projects & Funding
Projects & funding information is unavailable.
Publications (22)
- Synthesis and Structure−Activity Relationship (SAR) of Hydroxypyridone-3-carboxamides against Orthopoxviruses Save
- Inside Front Cover: Breakthrough Design of Highly Potent Antivirals Against Wild‐Type HIV‐1 and Lenacapavir‐Resistant M66I Variant Save
- Inside Front Cover: Breakthrough Design of Highly Potent Antivirals Against Wild‐Type HIV‐1 and Lenacapavir‐Resistant M66I Variant Save
- Breakthrough Design of Highly Potent Antivirals Against Wild‐Type HIV‐1 and Lenacapavir‐Resistant M66I Variant Save
- Breakthrough Design of Highly Potent Antivirals Against Wild‐Type HIV‐1 and Lenacapavir‐Resistant M66I Variant Save
- Norditerpene Natural Products from Subterranean Fungi with Anti-Parasitic Activity Save
- Methylation Enables Sensitive LC-MS/MS Quantification of Ciclopirox in a Mouse Pharmacokinetics Study Save
- Bioavailability enhancement of formononetin by incorporation of natural bioenhancer in phospholipid complex Save
- Augmented experimental design for bioavailability enhancement: a robust formulation of abiraterone acetate Save
- Cissus quadrangularis extract mitigates diabetic cardiomyopathy by inhibiting RAAS activation, inflammation and oxidative stress Save
- Diosmin, a citrus fruit-derived phlebotonic bioflavonoid protects rats from chronic kidney disease-induced loss of bone mass and strength without deteriorating the renal function. Save
- Evaluation of the Pharmacokinetics of the Pancreastatin Inhibitor PSTi8 Peptide in Rats: Integration of In Vitro and In Vivo Findings. Save
- Emerging nanotechnology based combination therapies of taxanes for multiple drug-resistant cancers Save
- Pancreastatin inhibitor PSTi8 prevents free fatty acid-induced oxidative stress and insulin resistance by modulating JNK pathway: In vitro and in vivo findings. Save
- Challenges of peptide and protein drug delivery by oral route: Current strategies to improve the bioavailability Save
- Pancreastatin mediated regulation of UCP-1 and energy expenditure in high fructose fed perimenopausal rats Save
- JNK signaling pathway in metabolic disorders: An emerging therapeutic target Save
- Herb–drug interaction studies of ethanolic extract of Cassia occidentalis L. coadministered with acetaminophen, theophylline, omeprazole, methotrexate and methylprednisolone Save
- PSTi8 with metformin ameliorates perimenopause induced steatohepatitis associated ER stress by regulating SIRT-1/SREBP-1c axis Save
- Simultaneous quantification of five biomarkers in ethanolic extract of Cassia occidentalis Linn. stem using liquid chromatography tandem mass spectrometry: application to its pharmacokinetic studies Save