Riyazuddin Mohammed

Employment

• University of Pittsburgh Postdoctoral Associate
  2024 - Present
• Vimta (India) Senior Research Scientist-I
  2023 - 2024
• Vimta (India) Scientist
  2022 - 2023
• Vimta Labs Ltd Senior Research Associate
  2019 - 2022

Education

• Central Drug Research Institute PhD
  2014 - 2019
• Indian Institute of Chemical Technology
  2014 - 2014
• Talla Padmavathi College of Pharmacy Master of Pharmacy
  2011 - 2013
• Catalyst Clinical Services Professional Diploma in Clinical Research
  2011 - 2012
• Nizam Institute of Pharmacy Bachelor of Pharmacy
  2007 - 2011

Projects & Funding

Projects & funding information is unavailable.

Publications (25)

• Herb–drug interaction studies of ethanolic extract of Cassia occidentalis L. coadministered with acetaminophen, theophylline, omeprazole, methotrexate and methylprednisolone
  Athar Husain, Mohammed Riyazuddin, Roshan A. Katekar

  +6 more

  • Saurabh Verma
  • Syed Anees Ahmed
  • Pragati Singh
  • Rakesh Maurya
  • Naibedya Chattopadhyay
  • +1 more
  Phytomedicine Plus 2021 DOI: 10.1016/j.phyplu.2020.100008
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• PSTi8 with metformin ameliorates perimenopause induced steatohepatitis associated ER stress by regulating SIRT-1/SREBP-1c axis
  Pragati Singh, Mohammad Irshad Reza, Anees A. Syed +7 more
  Heliyon 2020 DOI: 10.1016/j.heliyon.2020.e05826
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• Combination of Pancreastatin inhibitor PSTi8 with metformin inhibits Fetuin-A in type 2 diabetic mice
  Pragati Singh, Richa Garg, Umesh Kumar Goand +6 more
  Heliyon 2020 DOI: 10.1016/j.heliyon.2020.e05133
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• Pancreastatin inhibitor PSTi8 protects the obesity associated skeletal muscle insulin resistance in diet induced streptozotocin-treated diabetic mice
  Anand P. Gupta, Richa Garg, Pragati Singh +6 more
  European Journal of Pharmacology 2020 DOI: 10.1016/j.ejphar.2020.173204
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• Skeletal restoration by phosphodiesterase 5 inhibitors in osteopenic mice: Evidence of osteoanabolic and osteoangiogenic effects of the drugs
  Subhashis Pal, Mamunur Rashid, Sandeep Kumar Singh +6 more
  Bone 2020 DOI: 10.1016/j.bone.2020.115305
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• Combination of clofazimine and imatinib for effective therapy of drug-resistant myeloid leukemia
  2020
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• LC-ESI-MS/MS assay development and validation of a novel antidiabetic peptide PSTi8 in mice plasma using SPE: An application to pharmacokinetics.
  Journal of Pharmaceutical and Biomedical Analysis 2020
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• Simultaneous quantification of five biomarkers in ethanolic extract of Cassia occidentalis Linn. stem using liquid chromatography tandem mass spectrometry: application to its pharmacokinetic studies
  Mohammed Riyazuddin, Athar Husain, Saurabh Verma +8 more
  RSC Advances 2020 DOI: 10.1039/C9RA07482A
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• Pharmacokinetics and brain targeting of trans-resveratrol loaded mixed micelles in rats following intravenous administration
  Pharmaceutical Development and Technology 2019
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• Development and validation of LC-MS/MS method for quantification of novel PP2A – β-catenin signalling inhibitor, S011-2111 in mice plasma: Application to its preclinical pharmacokinetic studies
  Mohammed Riyazuddin, Athar Husain, Guru Raghavendra Valicherla +8 more
  Journal of Chromatography B 2019 DOI: 10.1016/j.jchromb.2019.121829
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• Pancreastatin inhibitor PSTi8 attenuates hyperinsulinemia induced obesity and inflammation mediated insulin resistance via MAPK/NOX3-JNK pathway.
  Anand P. Gupta, Anees A. Syed, Richa Garg +6 more
  European journal of pharmacology 2019 DOI: 10.1016/j.ejphar.2019.172723
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• Pancreastatin inhibitor, PSTi8 ameliorates metabolic health by modulating AKT/GSK-3β and PKCλ/ζ/SREBP1c pathways in high fat diet induced insulin resistance in peri-/post-menopausal rats
  Guru Raghavendra Valicherla, Anand P. Gupta, Zakir Hossain +6 more
  Peptides 2019 DOI: 10.1016/j.peptides.2019.170147
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• Leprosy drug clofazimine activates peroxisome proliferator-activated receptor-γ and synergizes with imatinib to inhibit chronic myeloid leukemia cells
  Harish Kumar, Sourav Chattopadhyay, Nabanita Das +22 more
  Haematologica 2019 DOI: 10.3324/haematol.2018.194910
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• Elucidation of pharmacokinetics of novel DNA ligase I inhibitor, S012-1332 in rats: Integration of in vitro and in vivo findings
  Mohammed Riyazuddin, Guru Raghavendra Valicherla, Athar Husain +8 more
  Journal of Pharmaceutical and Biomedical Analysis 2019 DOI: 10.1016/j.jpba.2018.09.031
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• Pancreastatin inhibitor activates AMPK pathway via GRP78 and ameliorates dexamethasone induced fatty liver disease in C57BL/6 mice
  Anand P. Gupta, Pragati Singh, Richa Garg +5 more
  Biomedicine and Pharmacotherapy 2019 DOI: 10.1016/j.biopha.2019.108959
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• Bioactive extract, fraction of Cassia Occidentalis and formulation thereof for bone regeneration
  2018
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• Discovery of pancreastatin inhibitor PSTi8 for the treatment of insulin resistance and diabetes: studies in rodent models of diabetes mellitus
  Zakir Hossain, Guru Raghavendra Valicherla, Anand P. Gupta +5 more
  Scientific Reports 2018 DOI: 10.1038/s41598-018-27018-8
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• Evaluation of oral pharmacokinetics, in vitro metabolism, blood partitioning and plasma protein binding of novel antidiabetic agent, S009-0629 in rats
  Guru Raghavendra Valicherla, Kishan Shamjibhai Italiya, Chandra Prakash Gupta +9 more
  Drug Development Research 2018 DOI: 10.1002/ddr.21433
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• Pancreastatin inhibitory peptides for the treatment of diabetes.
  2018
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• Isoalantolactone derivative promotes glucose utilization in skeletal muscle cells and increases energy expenditure in db/db mice via activating AMPK-dependent signaling.
  Deepti Arha, Eppalapally Ramakrishna, Anand P. Gupta +7 more
  Molecular and cellular endocrinology 2018 DOI: 10.1016/j.mce.2017.07.015
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