IK
I. Can Kazan
Also known as: Ismail Can Kazan, John Kazan
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Protein Structure and Dynamics · Evolution and Genetic Dynamics · SARS-CoV-2 and COVID-19 Research
0000-0003-2593-4179
Employment
Employment history is unavailable.
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (21)
- A protein dynamics–based deep learning model enhances predictions of fitness and epistasis Save
- Long-range coupling regulates stator dynamics in the bacterial flagellar motor Save
- Evidence that the cold- and menthol-sensing functions of the human TRPM8 channel evolved separately Save
- Some mechanistic underpinnings of molecular adaptations of SARS-COV-2 spike protein by integrating candidate adaptive polymorphisms with protein dynamics Save
- Engineering gain‐of‐function mutants of a WW domain by dynamics and structural analysis Save
- Allosteric regulatory control in dihydrofolate reductase is revealed by dynamic asymmetry Save
- Track: Protein and Ligand - A New Marriage Between an Old Couple Functional Ancestral Reconstruction of the Cold and Menthol Sensor TRPM8 Save
- Dynamic coupling of residues within proteins as a mechanistic foundation of many enigmatic pathogenic missense variants Save
- Investigating the allosteric response of the PICK1 PDZ domain to different ligands with all-atom simulations Save
- The Role of Rigid Residues in Modulating TEM-1 β-Lactamase Function and Thermostability Save
- Protein folding stability and binding interactions through the lens of evolution: a dynamical perspective Save
- Adaptive Evolution of SARS-CoV-2: A Perspective from Dynamics Save
- Design of novel Cyanovirin-N variants by modulation of binding dynamics through distal mutations Save
- A Method for the Incorporation of Protein Dynamics into Computational Enzyme Design using the Rosetta Software Suite Save
- Large Scale Disease Susceptibility Prediction of nSNVs by Dynamics Information Based Neural Networks Save
- DESIGN OF NOVEL LECTINS BY COMPUTER-AIDED DIRECTED EVOLUTION Save
- Coevolving residues inform protein dynamics profiles and disease susceptibility of nSNVs Save
- Design of Novel Lectins by Computer-Guided Directed Evolution Save
- Engineering Targeted Lectins by Computer-Guided Directed Evolution Save
- Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity (vol 7, 10419, 2017) Save