Kohei Kume

Employment

• Yale University Research Scientist
  2024 - Present

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (19)

• Dynamic feedback control of oncogenic tyrosine kinase signaling in acute leukemia
  Science Signaling 2026 DOI: 10.1126/scisignal.adw5054
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• Targeting β-catenin degradation with GSK3β inhibitors induces cell death in acute lymphoblastic leukemia
  Nature Cancer 2026 DOI: 10.1038/s43018-025-01093-z
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• Targeted Dynamic Phospho-Proteogenomic Analysis of Gastric Cancer Cells Suggests Host Immunity Provides Survival Benefit
  Molecular & Cellular Proteomics 2024 DOI: 10.1016/j.mcpro.2024.100870
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• Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer
  Teresa Sadras, Mickaël Martin, Kohei Kume

  +27 more

  • Mark E. Robinson
  • Supraja Saravanakumar
  • Gal Lenz
  • Zhengshan Chen
  • Joo Young Song
  • +22 more
  Molecular Cell 2021 DOI: 10.1016/j.molcel.2021.03.043
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• Circulating-tumor DNA from Two Types of Blood Collection Tubes for Monitoring Tumor Burden Validated with Esophageal Squamous Cell Carcinoma Patients
  2020 DOI: 10.1101/2020.08.12.20173070
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• Signalling input from divergent pathways subverts B cell transformation
  Nature 2020 DOI: 10.1038/s41586-020-2513-4
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• Colony Lysate Arrays for Proteomic Profiling of Drug-Tolerant Persisters of Cancer Cell
  Analytical Chemistry 2017 DOI: 10.1021/acs.analchem.7b01215
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• Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil
  Scientific Reports 2017 DOI: 10.1038/s41598-017-02548-9
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• Ductular reactions in the liver regeneration process with local inflammation after physical partial hepatectomy
  Laboratory Investigation 2016 DOI: 10.1038/labinvest.2016.97
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• Identification and functional analysis of SVP ortholog in herbaceous perennial plant Gentiana triflora: Implication for its multifunctional roles
  Plant Science 2016 DOI: 10.1016/j.plantsci.2016.04.003
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• α-Amanitin Restrains Cancer Relapse from Drug-Tolerant Cell Subpopulations via TAF15
  Scientific Reports 2016 DOI: 10.1038/srep25895
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• Individualized Mutation Detection in Circulating Tumor DNA for Monitoring Colorectal Tumor Burden Using a Cancer-Associated Gene Sequencing Panel
  PLOS ONE 2016 DOI: 10.1371/journal.pone.0146275
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• Downregulation of ST6GALNAC1 is associated with esophageal squamous cell carcinoma development
  International Journal of Oncology 2016 DOI: 10.3892/ijo.2016.3817
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• Systematic Protein Level Regulation via Degradation Machinery Induced by Genotoxic Drugs
  Journal of Proteome Research 2015 DOI: 10.1021/acs.jproteome.5b00759
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• A Compensatory Role of NF-κB to p53 in Response to 5-FU–Based Chemotherapy for Gastric Cancer Cell Lines
  PLoS ONE 2014 DOI: 10.1371/journal.pone.0090155
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• Contrasting Expression Patterns of Histone mRNA and microRNA 760 in Patients with Gastric Cancer
  Clinical Cancer Research 2013 DOI: 10.1158/1078-0432.ccr-12-3186
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• Evaluation of chemosensitivity prediction using quantitative dose–response curve classification for highly advanced/relapsed gastric cancer
  World Journal of Surgical Oncology 2013 DOI: 10.1186/1477-7819-11-11
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• W14/15 esterase gene haplotype can be a genetic landmark of cultivars and species of the genus Gentiana L
  Molecular Genetics and Genomics 2010 DOI: 10.1007/s00438-010-0582-z
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• TAS1trans-Acting siRNA Targets Are Differentially Regulated at Low Temperature, and TAS1trans-Acting siRNA Mediates Temperature-Controlled At1g51670 Expression
  Bioscience, Biotechnology, and Biochemistry 2010 DOI: 10.1271/bbb.100111
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