PK
Pallavi Kaila Sharma
University of California San Diego
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Protein Structure and Dynamics · Protein Kinase Regulation and GTPase Signaling · Enzyme Catalysis and Immobilization
0000-0003-2986-3515
Employment
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University of California San Diego Postdoctoral Researcher2019 - Present
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (10)
- Selective knockout of PKA regulatory subunits reveal opposite catalytic and metabolic consequences with implications for Alzheimer’s disease Save
- RedOx regulation of LRRK2 kinase activity by active site cysteines Save
- Understanding the role of the LRRK2 tail in the crosstalk between kinase and the N-terminal domains Save
- Novel LRR-ROC Motif That Links the N- and C-terminal Domains in LRRK2 Undergoes an Order–Disorder Transition Upon Activation Save
- Exploring the novel mechanistic aspects of function of a hyperthermophile two‐site exo‐amylase‐cum‐glucanotransferase displaying substrate versatility Save
- Exploring the novel mechanistic aspects of function of a hyperthermophile two-site exo-amylase-cum-glucanotransferase displaying substrate versatility Save
- LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains Save
- Kinase Domain Is a Dynamic Hub for Driving LRRK2 Allostery Save
- Creation of active TIM barrel enzymes through genetic fusion of half-barrel domain constructs derived from two distantly related glycosyl hydrolases Save
- Two helices control the dynamic crosstalk between the catalytic domains of LRRK2 Save