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Changuk Chung
University of California San Diego, Korea Advanced Institute of Science and Technology
Research areas: Biochemistry, Genetics and Molecular Biology · Genetics · Genetics and Neurodevelopmental Disorders · Autism Spectrum Disorder Research · Neuroscience and Neuropharmacology Research
0000-0003-3628-6090
Employment
- 2019 - Present
Education
- 2012 - 2017
- 2008 - 2012
Projects & Funding
-
Genetic and Molecular Etiology of Focal Cortical Dysplasia Brain and Behavior Research Foundation2022 - 2023
Publications (19)
- A comparative view of human and mouse telencephalon inhibitory neuron development Save
- Cell-type-resolved mosaicism reveals clonal dynamics of the human forebrain Save
- Control-independent mosaic single nucleotide variant detection with DeepMosaic Save
- Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability. Save
- Comprehensive multiomic profiling of somatic mutations in malformations of cortical development Save
- Somatic mosaicism reveals clonal distributions of neocortical development Save
- Early and late corrections in mouse models of autism spectrum disorders Save
- A human pleiotropic multiorgan condition caused by deficient Wnt secretion Save
- Early Chronic Memantine Treatment-Induced Transcriptomic Changes in Wild-Type and Shank2-Mutant Mice Save
- Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice Save
- DeepMosaic: Control-independent mosaic single nucleotide variant detection using deep convolutional neural networks Save
- Early Correction of N-Methyl-D-Aspartate Receptor Function Improves Autistic-like Social Behaviors in Adult Shank2 −/− Mice Save
- Lrfn2-Mutant Mice Display Suppressed Synaptic Plasticity and Inhibitory Synapse Development and Abnormal Social Communication and Startle Response Save
- Cell-Type-SpecificShank2Deletion in Mice Leads to Differential Synaptic and Behavioral Phenotypes Save
- Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice Save
- Cerebellar shank2 regulates excitatory synapse density, motor coordination, and specific repetitive and anxiety-like behaviors Save
- Shank3-mutant mice lacking exon 9 show altered excitation/inhibition balance, enhanced rearing, and spatial memory deficit Save
- Trans-synaptic zinc mobilization improves social interaction in two mouse models of autism through NMDAR activation Save
- Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function Save