W. Jonathan Lin

Employment

Employment history is unavailable.

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (6)

• Commonality of Mechanism in Glycoside Hydrolases, Nucleoside Hydrolases, and Phosphorylases: Importance of Side-Chain Conformation Preorganization
  Po‐Sen Tseng, Jonathan C.K. Quirke, Winston C. Lin +1 more
  JACS Au 2025 1 citation DOI: 10.1021/jacsau.5c01069
  +Save
• Structure of human MUTYH and functional profiling of cancer-associated variants reveal an allosteric network between its [4Fe-4S] cluster cofactor and active site required for DNA repair
  Carlos H. Trasviña‐Arenas, Upeksha C. Dissanayake, Nikole Tamayo +8 more
  Nature Communications 2025 22 citations DOI: 10.1038/s41467-025-58361-w
  +Save
• Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism
  Merve Demir, L. Peyton Russelburg, W. Jonathan Lin +5 more
  Nucleic Acids Research 2023 28 citations DOI: 10.1093/nar/gkac1246
  +Save
• The Dawn of a New Era in Drug Discovery? Drug Screening and the Increasing Biological Complexity of Testing Models
  W. Jonathan Lin
  Chemical Research in Toxicology 2021 1 citation DOI: 10.1021/acs.chemrestox.1c00331
  +Save
• Structure, function and evolution of the Helix-hairpin-Helix DNA glycosylase superfamily: Piecing together the evolutionary puzzle of DNA base damage repair mechanisms
  Carlos H. Trasviña‐Arenas, Merve Demir, Wen-Jen Lin +1 more
  DNA Repair 2021 42 citations DOI: 10.1016/j.dnarep.2021.103231
  +Save
• Structural Insights into the Mechanism of Base Excision by MBD4
  Lakshmi Swarna Mukhi Pidugu, Hilary Bright, Wen-Jen Lin +5 more
  Journal of Molecular Biology 2021 24 citations DOI: 10.1016/j.jmb.2021.167097
  +Save