SC
SANGITA CHOWDHURY
TCG Crest, Central Drug Research Institute
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Ubiquitin and proteasome pathways · Estrogen and related hormone effects · Immune cells in cancer
Employment
- 2026 - Present
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Central Drug Research Institute Senior Research Fellow2023 - Present
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Central Drug Research Institute Junior Research Fellow2021 - 2023
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (13)
- GSK3β-FBXW7 axis regulates MAFB protein stability through ubiquitin-mediated proteasome degradation Save
- Nemo‐like kinase modulates glucocorticoid‐induced erythroid progenitor differentiation by regulating stability of the glucocorticoid receptor Save
- Design, Synthesis, and Biological Evaluation of Thiourea‐Based Colchicine Derivatives as Proteasome Inhibitors in Cancer Therapy Save
- DARPP-32 is a novel regulator of M2-macrophage polarization: Sustains STAT6 phosphorylation by directly binding and inhibiting tyrosine phosphatase SHP-1 Save
- USP10 deubiquitinates and stabilizes CD44 leading to enhanced breast cancer cell proliferation, stemness and metastasis. Save
- Nemo-like kinase blocks myeloid differentiation by targeting tumor suppressor C/EBPα in AML. Save
- Hakai, a novel Runx2 interacting protein, augments osteoblast differentiation by rescuing Runx2 from Smurf2-mediated proteasome degradation. Save
- Ring finger protein 138 inhibits transcription factor C/EBPα protein turnover leading to differentiation arrest in acute myeloid leukemia. Save
- RING finger E3 ligase, RNF138 inhibits osteoblast differentiation by negatively regulating Runx2 protein turnover. Save
- Metabolic Regulation of Inflammation Save
- AIP4 regulates adipocyte differentiation by targeting C/EBPα for ubiquitin-mediated proteasomal degradation. Save
- Dexamethasone activates c-Jun NH2-terminal kinase (JNK) which interacts with GR and protects it from ubiquitin-mediated degradation in NSCLC cells. Save
- Origin, production and molecular determinants of macrophages for their therapeutic targeting. Save