Radhakrishnan K. V.
Also known as: Radhakrishnan Kokkuvayil Vasu
THIRUVANANTHAPURAM, University of Kerala, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram (formerly RRL)), • M.Sc. Chemistry
Research areas: Chemistry · Organic Chemistry · Organic Chemistry Synthesis Methods · Crystal structures of chemical compounds · Crystallography and molecular interactions
0000-0001-8909-3175
About
Dr. K. V. Radhakrishnan was born in Kerala, India. He received his B.Sc. and M.Sc. degrees from Christ College, Irinjalakuda, Kerala, India (University of Calicut), and Master of Human Resource Management (MHRM) from University of Kerala. He obtained his Ph.D. degree in synthetic organic chemistry from the University of Kerala in 1998 under the supervision of Dr. Vijay Nair at CSIR-NIIST, Trivandrum. Subsequently he held postdoctoral positions at Tohoku University, Sendai, Japan, with Professor Yoshinori Yamamoto; at the Molecumetics Institute, Bellevue, WA, with Professor Michael Kahn, and at NPG Research Institute, Raleigh, NC, with Professor Bert Fraser-Reid. He joined CSIR-NIIST as a Scientist in the Chemical Sciences and Technology Division in May 2002. His research interests include the development of novel synthetic methodologies utilizing pentafulvenes as synthons, synthetic carbohydrate chemistry, transition metal-catalyzed organic transformations toward pharmaceutically important molecules, and phytochemistry with special focus on bioprospecting of medicinal plants from Western Ghats. In addition to the above, he is an active participant in a number of collaborative projects in the process development of functional organic materials, APIs, agrochemicals, chemical intermediates and nutraceutical products for use in a variety of applications.
Employment
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THIRUVANANTHAPURAM Scientist2002 - Present
Education
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University of Kerala MHRM (Master of Human Resource Management)2014 - 2016
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CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram (formerly RRL)) Ph. D1993 - 1998
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• M.Sc. Chemistry M. Sc Chemistry1992 - 1994
Projects & Funding
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NWP-55-Organic light emitting Diodes (OLED) CSIR2012 - 2017
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Innovative Processes and Technologies for Agrochemicals (PI) CSIR
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Sustainable utilization of abundant natural resources: Synthetic Transformations of zerumbone and germacrone towards chemically diverse sesquiterpenoid Architectures (PI) Department of Science and Technology, Ministry of Science and Technology, India
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Screening of spices for activity against neurodegenerative diseases: A three tier screening approach employing in vitro and in vivo systems (PI) CSIR
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Organic reactions in generating innovative and natural scaffolds CSIR-Network project
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Transition metal/Lewis acid mediated reactions of strained diazanorbornenes and carbonyl compounds: Efficient access to biologically relevant scaffolds Department of Science and Technology, Ministry of Science and Technology, India
Publications (152)
- A Scientific Approach Towards Phyto-pharmacognostical Profiling of Coptis teeta Wall. Rhizome with Prominent Antioxidant Activity Save
- Simultaneous exploitation of phaeanthine – a bisbenzylisoquinoline alkaloid for dual anti-metastatic and anti-angiogenic potential by disruption of Akt/NF-κB/MMP regulatory pathways Save
- Exploring the hidden treasures of Coptis teeta Wall.: Ethnomedicinal claims, traditional wisdom and promising avenues for research Save
- Natural Prenylflavones from the Stem Bark of Artocarpus altilis: Promising Anticancer Agents for Oral Squamous Cell Carcinoma Targeting the Akt/mTOR/STAT-3 Signaling Pathway Save
- Protective effect of Pterospermum rubiginosum bark extract on bone mineral density and bone remodelling in estrogen deficient ovariectomized Sprague–Dawley (SD) rats Save
- A comprehensive apoptotic assessment of niloticin in cervical cancer cells: a tirucallane-type triterpenoid from Aphanamixis polystachya (Wall.) Parker Save
- Exploring apoptotic induction of malabaricone A in triple-negative breast cancer cells: an acylphenol phyto-entity isolated from the fruit rind of Myristica malabarica Lam. Save
- α/β-Stereo- and diastereoselective glycosylation with n-pentenyl glycoside donors, promoted by N-iodosuccinimide and catalyzed by chiral Brønsted acid Save
- Exploration of Phaeanthine: A Bisbenzylisoquinoline Alkaloid Induces Anticancer Effect in Cervical Cancer Cells Involving Mitochondria-Mediated Apoptosis Save
- Exploring the Phytochemical Profile and Biological Activities of Clerodendrum infortunatum Save
- Development of an oxyresveratrol incorporated bio-based smart nanocomposite coating with anti-corrosive, self-healing, and anti-microbial properties Save
- Developing the Natural Prenylflavone Artocarpin from Artocarpus hirsutus as a Potential Lead Targeting Pathogenic, Multidrug-Resistant Staphylococcus aureus, Persisters and Biofilms with No Detectable Resistance Save
- Plant derived bioactive compounds and their potential to enhance adult neurogenesis Save
- Transition Metal/Lewis Acid Catalyzed Reactions of Zerumbone for Diverse Molecular Motifs Save
- Cudraflavone C from Artocarpus hirsutus as a Promising Inhibitor of Pathogenic, Multidrug-Resistant S. aureus, Persisters, and Biofilms: A New Insight into a Rational Explanation of Traditional Wisdom Save
- Antiproliferative labdane diterpenes from the rhizomes of Hedychium flavescens Carey ex Roscoe Save
- Novel Flavonoids from the aerial parts of Unexplored and Endangered Wild nutmeg Species Myristica beddomei subsp. spherocarpa W.J. de Wilde Save
- Organic Brønsted acid‐catalyzed cycloadditions of o‐quinone methides with 1, 3‐dicarbonlys: Facile access to xanthenones and chromanones Save
- Tandem Photoisomerization and Transannular Cyclizations of Zerumbone Epoxide: A Model for Diversity-Oriented Synthesis Using Abundant Natural Products Save
- Mirabijalones S-W, rotenoids from rhizomes of white Mirabilis jalapa Linn. and their cell proliferative studies Save