Jianlin Xu

Employment

• Sanofi
  2023 - Present
• Bristol-Myers Squibb Company
  2006 - 2023
• Emergent BioSolutions Inc
  2004 - 2006
• Nereus Pharmaceuticals
  2003 - 2004
• Pennsylvania State University
  2001 - 2003

Education

• Ghent University Ph.D.
  1996 - 2001

Projects & Funding

Projects & funding information is unavailable.

Publications (22)

• Cysteine-condensed thiazolidine as an effective cysteine source for CHO cell culture
  Journal of Biotechnology 2026 DOI: 10.1016/j.jbiotec.2026.08.007
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• Recent advances in upstream process development for production of recombinant adeno‐associated virus
  Biotechnology and Bioengineering 2024 DOI: 10.1002/bit.28545
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• An adaptive modeling approach using spiking‐augmentation method to improve chemometric model performance in bioprocess monitoring
  Biotechnology Progress 2023 DOI: 10.1002/btpr.3349
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• Strategies for controlling afucosylation in monoclonal antibodies during upstream manufacturing
  Biotechnology Journal 2023 DOI: 10.1002/biot.202200604
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• Identification of Cell Culture Factors Influencing Afucosylation Levels in Monoclonal Antibodies by Partial Least-Squares Regression and Variable Importance Metrics
  Processes 2023 DOI: 10.3390/pr11010223
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• Upstream cell culture process characterization and in-process control strategy development at pandemic speed
  mAbs 2022 DOI: 10.1080/19420862.2022.2060724
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• Antibody charge variant modulation by in vitro enzymatic treatment in different Chinese hamster ovary cell cultures
  Jianlin Xu, Johanna Santos, Nadine S. Anderson +3 more
  Biotechnology Progress 2022 DOI: 10.1002/btpr.3268
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• Impact of preparation pH and temperature on amino acid stability of highly concentrated cell culture feed media
  Wanyue Cui, Jianfa Ou, Jianlin Xu +5 more
  Journal of Chemical Technology & Biotechnology 2022 DOI: 10.1002/jctb.7078
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• Improved Titer in Late-Stage Mammalian Cell Culture Manufacturing by Re-Cloning
  Qin He, Matthew S. Rehmann, Jun Tian +13 more
  Bioengineering 2022 DOI: 10.3390/bioengineering9040173
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• Insights into the Impact of Rosmarinic Acid on CHO Cell Culture Improvement through Transcriptomics Analysis
  Zhuangrong Huang, Jianlin Xu, Jun Tian +5 more
  Processes 2022 DOI: 10.3390/pr10030533
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• N-1 Perfusion Platform Development Using a Capacitance Probe for Biomanufacturing
  Emily S. C. Rittershaus, Matthew S. Rehmann, Jianlin Xu +6 more
  Bioengineering 2022 DOI: 10.3390/bioengineering9040128
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• High throughput screening data for a case study of CHO cell culture process development
  Qin He, Jianlin Xu, Erik Vandermark +7 more
  Data in Brief 2021 DOI: 10.1016/j.dib.2021.107491
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• Productivity improvement and charge variant modulation for intensified cell culture processes by adding a carboxypeptidase B (CpB) treatment step
  Jianlin Xu, Shun Zheng, Zeinab Dawood +8 more
  Biotechnology and Bioengineering 2021 DOI: 10.1002/bit.27723
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• New insights into genetic instability of an industrial CHO cell line by orthogonal omics
  Biochemical Engineering Journal 2020 DOI: 10.1016/j.bej.2020.107799
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• CHO cell productivity improvement by genome-scale modeling and pathway analysis: Application to feed supplements
  Zhuangrong Huang, Jianlin Xu, Andrew Yongky +6 more
  Biochemical Engineering Journal 2020 DOI: 10.1016/j.bej.2020.107638
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• Rosmarinic acid, a new raw material, doubled monoclonal antibody titer in cell culture manufacturing
  Jianlin Xu, Matthew S. Rehmann, Jun Tian +5 more
  Biochemical Engineering Journal 2020 DOI: 10.1016/j.bej.2020.107637
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• Effective temperature shift strategy development and scale confirmation for simultaneous optimization of protein productivity and quality in Chinese hamster ovary cells
  Biotechnology Progress 2020 DOI: 10.1002/btpr.2959
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• Kinetic modeling of Chinese hamster ovary cell culture: factors and principles
  Peifeng Tang, Jianlin Xu, Alastair Louey +6 more
  Critical Reviews in Biotechnology 2020 DOI: 10.1080/07388551.2019.1711015
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• Biomanufacturing evolution from conventional to intensified processes for productivity improvement: a case study
  mAbs 2020 DOI: 10.1080/19420862.2020.1770669
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• Process intensification in fed-batch production bioreactors using non-perfusion seed cultures
  Andrew Yongky, Jianlin Xu, Jun Tian +5 more
  mAbs 2019 DOI: 10.1080/19420862.2019.1652075
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