Zhuangrong Huang

Employment

• Bristol-Myers Squibb
  2019 - Present

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (32)

• An innovative hybrid modeling approach for simultaneous prediction of cell culture process dynamics and product quality
  Biotechnology Journal 2024 DOI: 10.1002/biot.202300473
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• Fed‐batch performance profiles for <scp>mAb</scp> production using different intensified N − 1 seed strategies are <scp>CHO</scp> cell‐line dependent
  Biotechnology Progress 2024 DOI: 10.1002/btpr.3446
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• Strategies for controlling afucosylation in monoclonal antibodies during upstream manufacturing
  Biotechnology Journal 2023 DOI: 10.1002/biot.202200604
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• Identification of Cell Culture Factors Influencing Afucosylation Levels in Monoclonal Antibodies by Partial Least-Squares Regression and Variable Importance Metrics
  Processes 2023 DOI: 10.3390/pr11010223
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• Insights into the Impact of Rosmarinic Acid on CHO Cell Culture Improvement through Transcriptomics Analysis
  Zhuangrong Huang, Jianlin Xu, Jun Tian +5 more
  Processes 2022 DOI: 10.3390/pr10030533
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• Bigdata analytics identifies metabolic inhibitors and promoters for productivity improvement and optimization of monoclonal antibody (mAb) production process
  Bioresources and Bioprocessing 2020 DOI: 10.1186/s40643-020-00318-6
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• CHO cell productivity improvement by genome-scale modeling and pathway analysis: Application to feed supplements
  Zhuangrong Huang, Jianlin Xu, Andrew Yongky +6 more
  Biochemical Engineering Journal 2020 DOI: 10.1016/j.bej.2020.107638
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• Identifying metabolic features and engineering targets for productivity improvement in CHO cells by integrated transcriptomics and genome-scale metabolic model
  Biochemical Engineering Journal 2020 DOI: 10.1016/j.bej.2020.107624
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• Primary concentration – The critical step in implementing the wastewater based epidemiology for the COVID-19 pandemic: A mini-review
  The Science of the total environment 2020
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• Integration of Time-Series Transcriptomic Data with Genome-Scale CHO Metabolic Models for mAb Engineering
  Processes 2020 DOI: 10.3390/pr8030331
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• Linking process variables to residence time distribution in a hybrid flowsheet model for continuous direct compression
  Chemical Engineering Research and Design 2020 DOI: 10.1016/j.cherd.2019.10.026
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• Treatment train approaches for the remediation of per- and polyfluoroalkyl substances (PFAS): A critical review.
  Journal of hazardous materials 2019 DOI: 10.1016/j.jhazmat.2019.121963
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• A Thermodynamic Balance Model for Liquid Film Drying Kinetics of a Tablet Film Coating and Drying Process.
  AAPS PharmSciTech 2019 DOI: 10.1208/s12249-019-1398-8
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• Integrated modeling of a continuous direct compression tablet manufacturing process: A production scale case study
  Powder Technology 2019 DOI: 10.1016/j.powtec.2019.05.078
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• Prediction of N-linked glycoform profiles of monoclonal antibody with extracellular metabolites and two-step intracellular models
  Processes 2019 DOI: 10.3390/pr7040227
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• Assessment of spatial heterogeneity in continuous twin screw wet granulation process using three-compartmental population balance model.
  Pharmaceutical development and technology 2018 DOI: 10.1080/10837450.2018.1427106
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• Modeling and simulation of continuous powder blending applied to a continuous direct compression process.
  Pharmaceutical development and technology 2018 DOI: 10.1080/10837450.2018.1425429
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• Mechanistic modeling and applications for CHO cell culture development and production
  Current Opinion in Chemical Engineering 2018 DOI: 10.1016/j.coche.2018.08.010
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• Prediction of critical quality attributes and optimization of continuous dry granulation process via flowsheet modeling and experimental validation
  Powder Technology 2018 DOI: 10.1016/j.powtec.2018.02.042
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• Kinetic Modeling of Mammalian Cell Culture Bioprocessing: The Quest to Advance Biomanufacturing.
  Biotechnology journal 2017 DOI: 10.1002/biot.201700229
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