KZ
Kam Zhang
RIKEN, Plexxikon (United States), Fred Hutchinson Cancer Research Center
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Protein Structure and Dynamics · Computational Drug Discovery Methods · Enzyme Structure and Function
0000-0002-9282-8045
Employment
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RIKEN Team Leader2009 - Present
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Plexxikon Inc Director2002 - 2008
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Fred Hutchinson Cancer Research Center Assistant Member1994 - 2001
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University of California Los Angeles Postdoctoral Research Fellow1989 - 1994
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (112)
- Mechanistic insights into the loss-of-function mechanisms of rare human D-amino acid oxidase variants implicated in amyotrophic lateral sclerosis Save
- Identification of a Selective RelA Inhibitor Based on DSE-FRET Screening Methods Save
- A protein sequence fitness function for identifying natural and nonnatural proteins Save
- Actin R256 Mono-methylation Is a Conserved Post-translational Modification Involved in Transcription Save
- A Series of Compounds Bearing a Dipyrido-Pyrimidine Scaffold Acting as Novel Human and Insect Pest Chitinase Inhibitors Save
- ATP7A Clinical Genetics Resource – A comprehensive clinically annotated database and resource for genetic variants in ATP7A gene Save
- EC313-a tissue selective SPRM reduces the growth and proliferation of uterine fibroids in a human uterine fibroid tissue xenograft model Save
- Improving ligand 3D shape similarity-based pose prediction with a continuum solvent model Save
- Human glutaminyl cyclase: Structure, function, inhibitors and involvement in Alzheimer’s disease Save
- EC359: A First-in-Class Small-Molecule Inhibitor for Targeting Oncogenic LIFR Signaling in Triple-Negative Breast Cancer Save
- A structural homology approach for computational protein design with flexible backbone Save
- Shape similarity guided pose prediction: lessons from D3R Grand Challenge 3 Save
- Human Chitinases: Structure, Function, and Inhibitor Discovery Save
- A cross docking pipeline for improving pose prediction and virtual screening performance Save
- Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity Save
- Identification and structure-activity relationship of purine derivatives as novel MTH1 inhibitors Save
- Balancing exploration and exploitation in population-based sampling improves fragment-basedde novoprotein structure prediction Save
- Discovery of Fungal Denitrification Inhibitors by Targeting Copper Nitrite Reductase fromFusarium oxysporum Save
- Evolution-Inspired Computational Design of Symmetric Proteins Save
- A Novel Scaffold for Developing Specific or Broad-Spectrum Chitinase Inhibitors Save