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Olga Kondrashova
QIMR Berghofer Medical Research Institute, Walter and Eliza Hall Institute of Medical Research
Research areas: Medicine · Oncology · Ovarian cancer diagnosis and treatment · BRCA gene mutations in cancer · PARP inhibition in cancer therapy
Employment
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QIMR Berghofer Medical Research Institute Team Head, Molecular Oncology2023 - Present
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QIMR Berghofer Medical Research Institute Postdoctoral scientist2019 - 2022
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Walter and Eliza Hall Institute of Medical Research Postdoctoral Fellow2016 - 2019
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (38)
- High-level tumour methylation of BRCA1 and RAD51C is required for homologous recombination deficiency in solid cancers Save
- Next batter up! Targeting cancers with KRAS-G12D mutations Save
- The microtubule inhibitor eribulin demonstrates efficacy in platinum-resistant and refractory high-grade serous ovarian cancer patient-derived xenograft models Save
- Performance of tumour microenvironment deconvolution methods in breast cancer using single-cell simulated bulk mixtures Save
- Multi-omic features of oesophageal adenocarcinoma in patients treated with preoperative neoadjuvant therapy Save
- Generalising uncertainty improves accuracy and safety of deep learning analytics applied to oncology. Save
- SpliceAI-10k calculator for the prediction of pseudoexonization, intron retention, and exon deletion. Save
- BRCA1secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance Save
- The Q-IMPROvE (Queensland-IMplementation of PRecision Oncology in brEast cancer) pilot study Save
- Heritable defects in telomere and mitotic function selectively predispose to sarcomas. Save
- Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin. Save
- Patient-derived xenograft models capture genomic heterogeneity in endometrial cancer Save
- Analysis of hereditary cancer gene variant classifications from ClinVar indicates a need for regular reassessment of clinical assertions. Save
- SpliceAI-10k calculator for the prediction of pseudoexonization, intron retention, and exon deletion Save
- Comparison of actionable events detected in cancer genomes by whole-genome sequencing, in silico whole-exome and mutation panels. Save
- Comprehensive genomic and tumour immune profiling reveals potential therapeutic targets in malignant pleural mesothelioma. Save
- Deep learning in cancer diagnosis, prognosis and treatment selection Save
- Acquired RAD51C Promoter Methylation Loss Causes PARP Inhibitor Resistance in High-Grade Serous Ovarian Carcinoma Save
- Characterization of a RAD51C-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance Save
- Tumor Signature Analysis Implicates Hereditary Cancer Genes in Endometrial Cancer Development Save