Pradeep Kumar
Banaras Hindu University, Lund University, Veer Bahadur Singh Purvanchal University
0000-0003-0081-3098
About
Dr. Pradeep Kumar is a Postdoctoral Researcher in the Department of Biology at Lund University, Sweden. His research integrates molecular biology, genetics, proteomics, and functional genomics to investigate the molecular mechanisms underlying cancer, neurodegeneration, and other complex diseases using Drosophila melanogaster as a model system.
He obtained his PhD in Plant Biotechnology from Banaras Hindu University, India, where his research focused on oncogenic RasV12-induced glioblastoma. His work identified novel mitochondrial dynamics regulators associated with glioblastoma progression and demonstrated the therapeutic potential of the chromene derivative 4H-CRCXL using integrated proteomic, biochemical, and in vivo approaches. He also investigated the neuroprotective effects of natural bioactive compounds in Drosophila models of Alzheimer's disease. These studies resulted in first-author publications in Journal of Proteome Research and Molecular Carcinogenesis.
His research interests include cancer biology, neurodegeneration, mitochondrial biology, developmental genetics, chronobiology, proteomics, systems biology, and translational drug discovery. He has expertise in LC-Orbitrap HRMS-based proteomics, Drosophila genetics, confocal microscopy, molecular biology, bioinformatics, and functional assays for therapeutic screening.
Dr. Kumar is interested in understanding the molecular basis of disease and translating fundamental biological discoveries into innovative therapeutic strategies. He welcomes interdisciplinary collaborations in molecular biology, genetics, proteomics, neurobiology, developmental biology, and translational biomedical research.
Employment
-
Banaras Hindu University Postdoctoral researcher2024 - Present
-
Lund University
Education
-
Banaras Hindu University Ph.D.2017 - 2024
-
Banaras Hindu University M.Sc.2015 - 2017
-
Veer Bahadur Singh Purvanchal University B.Sc.2012 - 2015
Projects & Funding
Projects & funding information is unavailable.
Publications (16)
- 4H‐CRCXL Mitigates RasV12‐Induced Phenotypes in Glioblastoma Model of Drosophila Save
- Insulin Producing Cells Specific dilp2 Knockdown Induced <scp>T1D</scp> Model Reveals Circadian and Oxidative Stress Associated <scp>DEPs</scp> Save
- A Stimuli Responsive Multifunctional Smart Luminophore with Aggregation-Induced Enhanced Emission Save
- Design, synthesis, and evaluation of benzhydrylpiperazine-based novel dual COX-2/5-LOX inhibitors with anti-inflammatory and anti-cancer activity Save
- LC-Orbitrap HRMS-Based Proteomics Reveals Novel Mitochondrial Dynamics Regulatory Proteins Associated with RasV12-Induced Glioblastoma (GBM) of Drosophila Save
- A coumarin derived turn ‘off–on-off’ probe for selective sequential monitoring of Al3+ and Cu2+ ions with bio-imaging application Save
- Design, synthesis, and biological evaluation of some 2-(3-oxo-5,6-diphenyl-1,2,4-triazin-2(3H)-yl)-N-phenylacetamide hybrids as MTDLs for Alzheimer's disease therapy Save
- Lead optimization based design, synthesis, and pharmacological evaluation of quinazoline derivatives as multi-targeting agents for Alzheimer's disease treatment Save
- Lysosome-targeting solid state NIR emissive donor–acceptor molecules: a study on photophysical modulation through architectural distinction Save
- Design and development of benzyl piperazine linked 5-phenyl-1,2,4-triazole-3-thione conjugates as potential agents to combat Alzheimer’s disease Save