chandana venkateswara rao
Research areas: Agricultural and Biological Sciences · Plant Science · Medicinal Plant Research · Drug-Induced Hepatotoxicity and Protection · Medicinal plant effects and applications
About
Dr. Ch. V. Rao is a Chief Scientist and Head of the Pharmacology Division at CSIR-National Botanical Research Institute, Lucknow. He is also a Professor of Biological Sciences (Pharmaceutical Sciences) at the Academy of Scientific & Innovative Research (AcSIR), a university promoted by CSIR and created through the act of parliament. He earned a Ph.D. in Pharmaceutical Sciences from Banaras Hindu University. Dr. Rao conducted postdoctoral research at AIIMS (All India Institute of Medical Sciences) Delhi.
Dr. Ch. V Rao is a distinguished researcher whose primary focus is developing herbal products and targeted drug delivery systems. With a strong pharmacology background, he explores herbal product development's fundamental and applied aspects. Driven by a passion for identifying potential herbal leads, he strives to create innovative solutions in medicine. Dr. Rao is a member of many professional bodies.
He also developed phage display technologies to generate fully human and identify bioactive compounds for various target diseases including metabolic and GIT infections. In recognition of his expertise, Dr. Rao has established a pharmacological laboratory for testing the safety and efficacy of herbal drugs and products using small animal models and cell lines. His dedication to research is evidenced by an impressive publication record, with over 195 original articles published in renowned journals. His innovative work has also resulted in 121 patents, including both granted and filed patents.
In addition to his research endeavors, Dr. Rao actively contributes to administering S&T activities at his institute.
As expertise in bio-prospection and product development from medicinal plants including lower and higher plants. In translational research, the products and herbal drugs were tested for safety and efficacy on various experimental models. The externally and internally funded project codes viz., GAP, HCP, MLP, OLP, and BSC have been implemented successfully as Co-ordinator, Principal Investigator, and Co-Principal Investigator. Major contributions involve the development of quality and pharmacological safety and efficacy studies viz Bureau of Indian Standards (BIS), AYUSH, ICMR, Pharmacopeia commission, TKDL, etc. In continuation developed IPR-covered herbal products and tested them against various animal models for safety and toxicity. One of the products gained attention and received a national award “Herbal Formulations for Management of Type-II Diabetes-NBRMAP”. Health care products like hand Sanitizer, toothpaste, gel, and IPR-covered products viz herbal Lip balm, herbal colors, hair dye, herbal drinks, etc have been tested for safety and toxicity and transferred to herbal Industries. Several patents were filed and published with supporting SCI publications during this period, and Ph.D. degrees were awarded. Know how technologies have been transferred/licensed to industrial partners. The skill-developed Programmes (SDP) were coordinated in herbal drugs and product development at the national level to trainee young entrepreneurs.
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Education
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Publications (20)
- Antioxidant, Antibacterial, and Antibiofilm Activities of Selected Medicinal Plant Extracts with In Vivo Protection against E. coli Infection Save
- Assessment of Toxicity and Wound Healing Activity of Selaginella Bryopteris Extract Save
- Bacteria‐Responsive Multidrug Delivery Nanosystem for Combating Long‐Term Biofilm‐Associated Infections Save
- The Role of Indian Magical Herb Selaginella bryopteris L. (Selaginaceae) in Pharmacotherapeutic Perspective: An Overview Save
- Wound Healing Activity of the Flavonoid-Enriched Fraction of Selaginella bryopteris Linn. against Streptozocin-Induced Diabetes in Rats Save
- Phenolics-Enriched Fraction of Pterospermum Lanceifolium Roxb. efficiently Reverses the Hepatocellular Carcinoma in NDEA-Induced HCC Rats Save
- Hepatoprotective and Antioxidant Potential of Phenolics-Enriched Fraction of Anogeissus acuminata Leaf against Alcohol-Induced Hepatotoxicity in Rats Save
- Nanocurcumin Potently Inhibits SARS-CoV-2 Spike Protein-Induced Cytokine Storm by Deactivation of MAPK/NF-κB Signaling in Epithelial Cells Save
- Cinnamomum verum-derived bioactives-functionalized gold nanoparticles for prevention of obesity through gut microbiota reshaping Save
- A machine learning-based approach to determine infection status in recipients of BBV152 whole virion inactivated SARS-CoV-2 vaccine for serological surveys Save
- Chrysophanol-Functionalized Silver Nanoparticles for Anti-Adhesive and Anti-Biofouling Coatings to Prevent Urinary Catheter-Associated Infections Save
- Hepatoprotective activity of depsidone enriched Cladonia rangiferina extract against alcohol-induced hepatotoxicity targeting cytochrome P450 2E1 induced oxidative damage Save
- Wound Healing Activity of Ethanolic Extract of Selaginella Bryopteris on Rats Save
- Oxidative free radicals scavenging activity (in vitro and in vivo assay) of standardized fractions from the seeds of Argyreia speciosa (Ghav-patta) a traditional Indian medicine Save
- ZnO/Curcumin Nanocomposites for Enhanced Inhibition of Pseudomonas aeruginosa Virulence via LasR-RhlR Quorum Sensing Systems Save
- Biogenic silver nanoparticles as a more efficient contrivance for wound healing acceleration than common antiseptic medicine Save
- Comprehensive Analysis of Secondary Metabolites in Usnea longissima (Lichenized Ascomycetes, Parmeliaceae) Using UPLC-ESI-QTOF-MS/MS and Pro-Apoptotic Activity of Barbatic Acid Save
- In vitro wound healing activity of 1-hydroxy-5,7-dimethoxy-2-naphthalene-carboxaldehyde (HDNC) and other isolates of Aegle marmelos L.: Enhances keratinocytes motility via Wnt/β-catenin and RAS-ERK pathways Save
- Formononetin and biochanin A protects against ritonavir induced hepatotoxicity via modulation of NfκB/pAkt signaling molecules Save
- Phytochemical investigation, antioxidant and wound healing activities of Citrullus colocynthis (bitter apple) Save