MO
Masato Ogishi
Stanford University, Rockefeller University, The University of Tokyo, The Institute of Medical Sciences Research Hospital, The University of Tokyo
Research areas: Immunology and Microbiology · Immunology · Immunodeficiency and Autoimmune Disorders · T-cell and B-cell Immunology · interferon and immune responses
Employment
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Stanford University Postdoctoral fellow2024 - Present
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Rockefeller University Graduate Fellow2018 - 2024
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The Institute of Medical Sciences Research Hospital, The University of Tokyo Research fellow2017 - 2018
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National Center for Global Health and Medicine Hospital Resident2016 - 2018
Education
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The Rockefeller University Ph.D. in Immunology2018 - 2024
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University of Tokyo Doctor of Medicine (M.D.)2010 - 2016
Projects & Funding
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Genetic and immunological dissection of coinhibitory crosstalks between human T cells and cancer cells National Cancer Institute2022 - 2023
Publications (57)
- Human-inherited RORγT deficiency encompasses genetic heterogeneity, T cell deficiency, and clinical homogeneity. Save
- Humans homozygous for rare or common hypomorphic IL23R variants are prone to tuberculosis Save
- Facile induction of immune tolerance by an interleukin-2–TGFβ surrogate agonist Save
- Overcoming T cell tolerance to tumor self-antigens through catch-bond engineering Save
- Human LFA-1 governs T cell immune surveillance of the skin Save
- Rewiring STAT signaling from the cell surface with Trikine immunotherapeutics Save
- Selective Immune Silencing by Targeted TGF-β Agonists. Save
- Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function Save
- Design of facilitated dissociation enables timing of cytokine signalling Save
- Expanding the cytokine receptor alphabet reprograms T cells into diverse states Save
- Human LY9 governs CD4+ T cell IFN-γ immunity to Mycobacterium tuberculosis Save
- Role of clonal inflammatory microglia in histiocytosis-associated neurodegeneration. Save
- Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling. Save
- Autoinflammation in patients with leukocytic CBL loss of heterozygosity is caused by constitutive ERK-mediated monocyte activation Save
- IL-7–dependent and –independent lineages of IL-7R–dependent human T cells Save
- A case of Darier's disease with a missense mutation in exon 8 of ATP2A2. Save
- Inherited human RelB deficiency impairs innate and adaptive immunity to infection Save
- Tuberculosis in otherwise healthy adults with inherited TNF deficiency. Save
- Human inherited PD-L1 deficiency is clinically and immunologically less severe than PD-1 deficiency. Save
- PD-1 signaling in neonates restrains CD8+T cell function and protects against respiratory viral immunopathology Save